Results 31 to 40 of about 3,726,940 (286)
An electrochemical immunosensor was fabricated to identify CA15-3, a biomarker for breast cancer (BC). A composite sensor substrate made of “zeolitic imidazolate framework-8” (ZIF-8) and “reduced graphene oxide” (rGO) was chosen and its conductivity was ...
Yuanyue Lu +8 more
doaj +1 more source
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
miR-29b-3p regulates cardiomyocytes pyroptosis in CVB3-induced myocarditis through targeting DNMT3A
Background Viral myocarditis (VMC) is a disease resulting from viral infection, which manifests as inflammation of myocardial cells. Until now, the treatment of VMC is still a great challenge for clinicians.
Ya Wang +5 more
doaj +1 more source
NAD+ reduces ventricular arrhythmias by inhibiting INaL and Ito in mice [PDF]
Objective: Decreased nicotinamide adenine dinucleotide (NAD+) levels are a common feature of cardiovascular diseases, exogenous NAD+ can also block myocardial hypertrophy responses in vivo and in vitro.
Liu Zhijie, Zhang Min, Luo Antao
doaj +1 more source
Biomarkers for hazard identification in humans [PDF]
Oxidative stress enhances lipid peroxidation (LPO), which both are implicated in the promotion and progression stages of carcinogenesis, in particular under conditions of chronic inflammation and infections. Exocyclic etheno-DNA adducts, which are formed by LPO-products such as 4-hydroxy -2-nonenal, are strongly pro-mutagenic DNA lesions.The ...
Bartsch, Helmut +2 more
openaire +2 more sources
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
In addition to process control at the equipment level, the Identification of systemic hazards and the realization of process safety are also part of the operational problems of complex systems.
Wu, Jing +3 more
core +1 more source
The Kansas Hazard Mitigation Strategy
Rev. 2.; application/pdf; "January 2002.""This document is a comprehensive strategy developed by the state agencies of Kansas to create an effective, long-term approach to eliminate or reduce the vulnerability of Kansas' communities to the human ...
Kansas Hazard Mitigation Team.
core +1 more source

