Results 11 to 20 of about 3,726,940 (286)

The hazards of hazard identification in environmental epidemiology [PDF]

open access: yesEnvironmental Health, 2017
Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process.
Saracci R.
openaire   +4 more sources

Key Characteristics Approach to Carcinogenic Hazard Identification. [PDF]

open access: yesChem Res Toxicol, 2018
Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to ...
Guyton KZ   +4 more
europepmc   +2 more sources

Development of a novel method for cross-disciplinary hazard identification [PDF]

open access: yes, 2013
Hazards and risks are currently identified in generic risk silos using top-down tools and methods which are incorporated into whole system risk management frameworks such as enterprise risk management.
Parchment, Ann
core   +7 more sources

Risks of benzalkonium chlorides as emerging contaminants in the environment and possible control strategies from the perspective of ecopharmacovigilance

open access: yesEcotoxicology and Environmental Safety, 2023
An unprecedented increase in the use of disinfection products triggered by the coronavirus disease 2019 (COVID-19) pandemic is resulting in aggravating environmental loads of disinfectants as emerging contaminants, which has been considered a cause for ...
Mengfan Liao   +4 more
doaj   +1 more source

TLR4 signaling in the development of colitis-associated cancer and its possible interplay with microRNA-155

open access: yesCell Communication and Signaling, 2021
Ulcerative colitis (UC) has closely been associated with an increased risk of colorectal cancer. However, the exact mechanisms underlying colitis-associated cancer (CAC) development remain unclear.
Jie Guo, Mengfan Liao, Jun Wang
doaj   +1 more source

The anti-apoptotic, antioxidant and anti-inflammatory effects of curcumin on acrylamide-induced neurotoxicity in rats

open access: yesBMC Pharmacology and Toxicology, 2020
Background Acrylamide (ACR) formed during heating of tobacco and carbohydrate-rich food as well as widely applied in industries has been known as a well-established neurotoxic pollutant.
Jie Guo   +4 more
doaj   +1 more source

Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy

open access: yesCell Death and Disease, 2022
Cadmium is one of the environmental and occupational pollutants and its potential adverse effects on human health have given rise to substantial concern. Cadmium causes damage to the male reproductive system via induction of germ-cell apoptosis; however,
Lingna Yi   +8 more
doaj   +1 more source

Protective effect of ethyl acetate fraction from Semen sojae germinatum, the processed sprout of Chinese black soybean, on rat experimental osteoarthritis

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Our previous in vitro study reported that the ethyl acetate fraction (EAF) of Semen sojae germinatum (SSG), the processed sprout of Chinese black soybean, possessed the potent anti-inflammatory and chondroprotective properties.
Jun Wang   +4 more
doaj   +1 more source

A method for computer-aided hazard identification of process plants [PDF]

open access: yes, 1986
A method for computer-aided hazard identification of process ...
Jayesh C. Parmar (7128032)
core   +5 more sources

Protective Effect of Curcumin on Acrylamide-Induced Hepatic and Renal Impairment in Rats: Involvement of CYP2E1

open access: yesNatural Product Communications, 2020
As a chemical extensively used in industrial areas and formed during heating of carbohydrate-rich foods and tobacco, acrylamide (ACR) has been demonstrated to exert a variety of systemic toxic effects including hepatotoxicity and nephrotoxicity.
Rui Sun   +4 more
doaj   +1 more source

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