Results 1 to 10 of about 4,142,780 (296)

Nanoplastics and Human Health: Hazard Identification and Biointerface. [PDF]

Nanomaterials (Basel), 2022
Nanoplastics are associated with several risks to the ecology and toxicity to humans. Nanoplastics are synthetic polymers with dimensions ranging from 1 nm to 1 μm.
Lai H, Liu X, Qu M.
europepmc   +2 more sources

Firefighting and Cancer: A Meta-analysis of Cohort Studies in the Context of Cancer Hazard Identification. [PDF]

Saf Health Work, 2023
Objective We performed a meta-analysis of epidemiological results for the association between occupational exposure as a firefighter and cancer as part of the broader evidence synthesis work of the IARCMonographs program.
DeBono NL, Daniels RD, Beane Freeman LE, Graber JM, Hansen J, Teras LR, Driscoll T, Kjaerheim K, Demers PA, Glass DC, Kriebel D, Kirkham TL, Wedekind R, Filho AM, Stayner L, Schubauer-Berigan MK.   +15 more
europepmc   +2 more sources

Consensus on the Key Characteristics of Immunotoxic Agents as a Basis for Hazard Identification. [PDF]

Environ Health Perspect, 2022
Background: Key characteristics (KCs), properties of agents or exposures that confer potential hazard, have been developed for carcinogens and other toxicant classes.
Germolec DR, Lebrec H, Anderson SE, Burleson GR, Cardenas A, Corsini E, Elmore SE, Kaplan BLF, Lawrence BP, Lehmann GM, Maier CC, McHale CM, Myers LP, Pallardy M, Rooney AA, Zeise L, Zhang L, Smith MT.   +17 more
europepmc   +2 more sources

Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application. [PDF]

Arch Toxicol, 2022
Risk assessments are increasingly reliant on information from in vitro assays. The in vitro micronucleus test (MNvit) is a genotoxicity test that detects chromosomal abnormalities, including chromosome breakage (clastogenicity) and/or whole chromosome ...
Kuo B, Beal MA, Wills JW, White PA, Marchetti F, Nong A, Barton-Maclaren TS, Houck K, Yauk CL.   +8 more
europepmc   +2 more sources

Effects of communicating uncertainty descriptions in hazard identification, risk characterization, and risk protection. [PDF]

PLoS One, 2021
Uncertainty is a crucial issue for any risk assessment. Consequently, it also poses crucial challenges for risk communications. Many guidebooks advise reporting uncertainties in risk assessments, expecting that the audience will appreciate this ...
Wiedemann P, Boerner FU, Freudenstein F.
europepmc   +2 more sources

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. [PDF]

Nat Rev Endocrinol, 2020
Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with hormone action, thereby increasing the risk of adverse health outcomes, including cancer, reproductive impairment, cognitive deficits and obesity.
La Merrill MA, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller RT.   +15 more
europepmc   +2 more sources

Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization. [PDF]

Expert Opin Drug Metab Toxicol, 2021
Introduction Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes is one of the most widely used cell-based models that resulted from the discovery of how non-embryonic stem cells can be differentiated into multiple cell types.
Burnett SD, Blanchette AD, Chiu WA, Rusyn I.   +3 more
europepmc   +2 more sources

Causality-Network-Based Critical Hazard Identification for Railway Accident Prevention: Complex Network-Based Model Development and Comparison. [PDF]

Entropy (Basel), 2021
This study investigates a critical hazard identification method for railway accident prevention. A new accident causation network is proposed to model the interaction between hazards and accidents.
Li Q, Zhang Z, Peng F.
europepmc   +2 more sources

The hazards of hazard identification in environmental epidemiology. [PDF]

Environ Health, 2017
Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process.
Saracci R.
europepmc   +5 more sources

The IARC Monographs: Updated Procedures for Modern and Transparent Evidence Synthesis in Cancer Hazard Identification. [PDF]

J Natl Cancer Inst, 2020
The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these
Samet JM, Chiu WA, Cogliano V, Jinot J, Kriebel D, Lunn RM, Beland FA, Bero L, Browne P, Fritschi L, Kanno J, Lachenmeier DW, Lan Q, Lasfargues G, Le Curieux F, Peters S, Shubat P, Sone H, White MC, Williamson J, Yakubovskaya M, Siemiatycki J, White PA, Guyton KZ, Schubauer-Berigan MK, Hall AL, Grosse Y, Bouvard V, Benbrahim-Tallaa L, El Ghissassi F, Lauby-Secretan B, Armstrong B, Saracci R, Zavadil J, Straif K, Wild CP.   +35 more
europepmc   +2 more sources