The restricted mean survival time as a replacement for the hazard ratio and the number needed to treat in long-term studies. [PDF]
Messori A, Bartoli L, Trippoli S.
europepmc +1 more source
Beyond Hazard Ratios: Appropriate statistical methods for quantifying the clinical effectiveness of immune-oncology therapies – the example of the Netherlands [PDF]
Isaac Corro Ramos +2 more
openalex +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Time dependent hazard ratio estimation using instrumental variables without conditioning on an omitted covariate. [PDF]
MacKenzie TA +2 more
europepmc +1 more source
A likelihood ratio test for monotone baseline hazard functions in the cox model [PDF]
Gabriela F. Nane
openalex +1 more source
Hedging Pure Endowments with Mortality Derivatives [PDF]
In recent years, a market for mortality derivatives began developing as a way to handle systematic mortality risk, which is inherent in life insurance and annuity contracts.
Wang, Ting, Young, Virginia R.
core
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Using the geometric average hazard ratio in sample size calculation for time-to-event data with composite endpoints. [PDF]
Cortés Martínez J +3 more
europepmc +1 more source
Magnitude of the Difference Between Clinic and Ambulatory Blood Pressures and Risk of Adverse Outcomes in Patients With Chronic Kidney Disease. [PDF]
Background Obtaining 24-hour ambulatory blood pressure ( BP ) is recommended for the detection of masked or white-coat hypertension. Our objective was to determine whether the magnitude of the difference between ambulatory and clinic BP s has prognostic ...
Bae, Se Ri +7 more
core +1 more source

