Results 271 to 280 of about 6,466,330 (328)

An explanation of the hazard ratio

Pharmaceutical Statistics, 2004
Several months ago someone attended a course for non-statisticians that I was running and said, ‘If I can go away from this course understanding what a hazard ratio is then it will have been worthwhile!’ Well, here goes. The hazard ratio, like the odds ratio, is not only difficult to explain but its use and interpretation continue to confuse both ...
R. Kay
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Nonparametric Estimation of the Hazard Ratio

Journal of the American Statistical Association, 1984
Abstract A nonparametric estimate of the hazard ratio function is developed and applied to the time-dependent survival advantage of having achieved an objective response to treatment for a given disease. The method computes the total exposure to risk of failure, or dying, among patients in either of two disease states (nonresponder/responder).
H. Thaler
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Interpreting hazard ratios

BMJ, 2015
The impact of isoniazid prophylaxis on mortality and tuberculosis in children with HIV was investigated using a double blind placebo controlled trial. The intervention was isoniazid given with co-trimoxazole either daily or three times a week. Control treatment was placebo isoniazid given with co-trimoxazole.
Philip, Sedgwick, Katherine, Joekes
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On the interpretation of the hazard ratio in Cox regression

Biometrical journal. Biometrische Zeitschrift, 2019
We argue that the term “relative risk” should not be used as a synonym for “hazard ratio” and encourage to use the probabilistic index as an alternative effect measure for Cox regression.
J. De Neve, T. Gerds
semanticscholar   +1 more source

Hazard Ratio Estimator

International Encyclopedia of Statistical Science, 2011
P. Andersen
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Hazards and hazard ratios

BMJ, 2012
Researchers investigated the risk of colorectal cancer after screening with flexible sigmoidoscopy. A randomised controlled study was undertaken in Norway with a population based sample. The intervention consisted of once only flexible sigmoidoscopy screening with or without a single round of faecal occult blood testing.
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Bayesian analysis for monotone hazard ratio

Lifetime Data Analysis, 2010
We propose a Bayesian approach for estimating the hazard functions under the constraint of a monotone hazard ratio. We construct a model for the monotone hazard ratio utilizing the Cox's proportional hazards model with a monotone time-dependent coefficient.
Kim, Yongdai, Park, Jin Kyung, Kim, Gwangsu   +2 more
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Hazards of Hazard Ratios — Deviations from Model Assumptions in Immunotherapy

New England Journal of Medicine, 2018
Look Beyond Hazard Ratios Many trials are based on the proportional-hazards assumption that an event is equally likely in different treatment groups over time and deviations are related to the intervention. Full Kaplan–Meier estimates from earlier trials may be more informative than summary statistics.
Brian M. Alexander, Jonathan D. Schoenfeld, Lorenzo Trippa   +2 more
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Estimating Monotonic Hazard Ratio Functions of Time

International Statistical Review, 2021
SummaryIn non‐proportional hazards models, the hazard ratio for a unit increase in covariate value is not constant but varies over time. Existing approaches to estimating time‐varying log hazard ratio include various spline approximations and maximum penalised partial likelihood.
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Hazard rate ratio and prospective epidemiological studies

Journal of Clinical Epidemiology, 2002
Analysis of prospective follow-up data usually includes a Cox regression model. When a hazard rate ratio, obtained as the exponential of an estimated regression coefficient from the Cox model, is greater than 1.0, it consistently exceeds relative risk, and is exceeded by the odds ratio.
M J, Symons, D T, Moore
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