Results 71 to 80 of about 238,148 (334)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Safety restrictions in the logistics of dangerous and toxic substances

open access: yesProduction Engineering Archives, 2015
In this work the difficulties of a safety restriction in the transport of chemical substances is explored. The ranking of dangerous substances and materials is presented to indicate that substances used in various industries have been called hazardous ...
Dorota Klimecka-Tatar
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Health care workers during the COVID-19 pandemic: prevalence of adverse skin reactions from using protective equipment

open access: yesSafety and Health at Work, 2022
Claudia Westermann   +5 more
doaj   +1 more source

MODELING OF THE BUILDING LOCAL PROTECTION (SHELTER – IN PLACE) INCLUDING SORBTION OF THE HAZARDOUS CONTAMINANT ON INDOOR SURFACES

open access: yesNauka ta progres transportu, 2014
Purpose. Chemically hazardous objects, where toxic substances are used, manufactured and stored, and also main lines, on which the hazardous materials transportation is conducted, pose potential sources of atmosphere accidental pollution.Development of ...
N. N. Belyayev   +2 more
doaj   +1 more source

ATSDR public health investment : Massachusetts [PDF]

open access: yes
CDC/ATSDR support Massachusetts to reduce exposure to hazardous substances in the environment ATSDR funds 25 cooperative agreements to help states build their capacity to assess and respond to site-specific issues involving human exposure to hazardous ...

core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

ATSDR public health investment : Wisconsin [PDF]

open access: yes
CDC/ATSDR support helps Wisconsin reduce exposures to hazardous substances in the environment ATSDR funds 25 cooperative agreements to help states build their capacity to assess and respond to site-specific issues involving human exposure to hazardous ...

core  

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