Results 141 to 150 of about 652,688 (313)
Global warming level indicators of climate change and hotspots of exposure
Environmental Research: ClimateIn the 21st century, a growing population will be exposed to various hazards caused by a warming climate. Here we present a new database of 12 climate change indicators with a total of 42 variants at different global warming levels (GWLs) (1.2 °C–3.5 °C),
Michaela Werning +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Oregon Pre-Disaster Mitigation: Training Manual
, 2003 This manual and training provides a process for developing as well as evaluating natural hazard mitigation plans. Additionally, this document and training synthesize the standards and approaches developed by state and federal agencies and organizations ...
LeDuc, Andre +1 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
HAZARD ANALYSIS AND ASSESSMENT OF OCCUPATIONAL RISK WITH STONE WORKS IN CONSTRUCTION
RUDN Journal of Ecology and Life Safety, 2015 The main dangerous and harmful factors of production in construction with stone work were analyzed, taking into account the features of this kind of economic activity. The occupational risk in the performance of stone works was evaluated.
F F Arslanbekova +2 more
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Reducing People?s Vulnerability to Natural Hazards: Communities and Resilience [PDF]
The concepts vulnerability, resilience and community are widely used and abused in the literature on natural hazards and disaster risk reduction. This paper seeks to bring greater rigour in their use.
Cannon, Terry
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Analysing vulnerability to volcanic hazards: application to St. Vincent
, 2010 Volcanology and volcanic risk assessment have in the past been strongly biased towards pure physical sciences and the study of hazard mechanisms. Traditional vulnerability analyses undertaken at volcanoes have focused on the vulnerability of buildings
Lowe, C.J.
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