Results 141 to 150 of about 1,363,199 (306)

L'hydrogéomorphologie appliquée à la gestion de l'aléa d'inondation en climat tempéré froid : l'exemple de la rivière Matane (Québec)

open access: yesPhysio-Géo, 2014
Sylvio Demers   +5 more
doaj   +1 more source

Global warming level indicators of climate change and hotspots of exposure

open access: yesEnvironmental Research: Climate
In the 21st century, a growing population will be exposed to various hazards caused by a warming climate. Here we present a new database of 12 climate change indicators with a total of 42 variants at different global warming levels (GWLs) (1.2 °C–3.5 °C),
Michaela Werning   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Hedging Strategies in Forest Management [PDF]

open access: yes
The paper focuses on forests management strategies for natural hazards of nonindustrial owners, in the case where the forest provides nontimber services.
Brunette, Marielle   +2 more
core   +1 more source

Radiation hazards [PDF]

open access: yesPostgraduate Medical Journal, 1966
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

HAZARD ANALYSIS AND ASSESSMENT OF OCCUPATIONAL RISK WITH STONE WORKS IN CONSTRUCTION

open access: yesRUDN Journal of Ecology and Life Safety, 2015
The main dangerous and harmful factors of production in construction with stone work were analyzed, taking into account the features of this kind of economic activity. The occupational risk in the performance of stone works was evaluated.
F F Arslanbekova   +2 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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