Results 91 to 100 of about 416,102 (337)

HEMOGLOBIN A1C IMPROVEMENTS AND BETTER DIABETES-SPECIFIC QUALITY OF LIFE AMONG PARTICIPANTS COMPLETING DIABETES SELF-MANAGEMENT PROGRAMS: A NESTED COHORT STUDY [PDF]

, 2018
Background: Numerous primary care innovations emphasize patient-centered processes of care. Within the context of these innovations, greater understanding is needed of the relationship between improvements in clinical endpoints and patient-centered ...
Khanna, Abhinav
core   +1 more source

The Effects of 810 nm Diode Laser and Indocyanine Green on Periodontal Parameters and HbA1c in Patients with Periodontitis and Type II Diabetes Mellitus: A Randomized Controlled Study [PDF]

, 2022
Irina-Georgeta Șufaru, Maria-Alexandra Mârțu, Ionuţ Luchian, Simona Stoleriu, Diana Diaconu-Popa, Cristian Mârţu, Silvia Teslaru, Liliana Păsărin, Sorina Mihaela Solomon   +8 more
openalex   +1 more source

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

Advanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng, Ruijie Xie, Bernd Holleczek, Hermann Brenner, Ben Schöttker   +4 more
wiley   +1 more source

HbA1c and Hypoglycemia Reductions at 24 and 52 Weeks With Sotagliflozin in Combination With Insulin in Adults With Type 1 Diabetes: The European inTandem2 Study

Diabetes Care, 2018
OBJECTIVE The objective of this study was to evaluate the efficacy and safety of the dual sodium–glucose cotransporter 1 and 2 inhibitor sotagliflozin compared with placebo when combined with optimized insulin in adults with type 1 diabetes (T1D ...
T. Danne, B. Cariou, Phillip L. Banks, M. Brandle, H. Brath, E. Franek, J. Kushner, P. Lapuerta, D. McGuire, A. Peters, Sangeeta Sawhney, P. Strumph   +11 more
semanticscholar   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Increased levels of serum Adenosine deaminase (ADA) enzyme and increased risk of T cell activation markers in type 2 diabetes [PDF]

Cellular, Molecular and Biomedical Reports
Diabetes Type 2 is the most common type of diabetes, a common disorder of glucose homeostasis and accounts for 90% of cases. The prevalence of diabetes type 2 is increasing. Adenosine deaminase is an enzymatic polymorphism that plays an important role in
Mahboobeh Talebi Mehrdar, Ghazale Ebadi
doaj   +1 more source

Thigh fat and muscle each contribute to excess cardiometabolic risk in South Asians, independent of visceral adipose tissue. [PDF]

, 2014
OBJECTIVE: To compare fat distribution and associations between fat depots and cardiometabolic traits in South Asians and Europeans. METHODS: Five hundred and fourteen South Asians and 669 Europeans, aged 56-86.
Chaturvedi, N, Eastwood, SV, Forouhi, NG, Godsland, I, Hughes, AD, Mayet, J, Tillin, T, Whincup, P, Wright, A   +8 more
core   +1 more source

Neonatal outcomes associated with high HbA1c prior to delivery [PDF]

, 2021
Matthew Brady, Rachel Paul, Antonina I. Frolova, Anthony Odibo, Jeannie C. Kelly, Nandini Raghuraman, Ebony B. Carter   +6 more
openalex   +1 more source

Evaluating the Effects of Canagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Chronic Kidney Disease According to Baseline HbA1c, Including Those with HbA1c <7%: Results From the CREDENCE Trial.

Circulation, 2019
Traditional management of diabetes mellitus has focused on glycemic control, beginning with lifestyle changes, followed by metformin, and then other classes of antiglycemic agents.1 Sodium glucose co-transporter 2 (SGLT2) inhibitors reduce cardiovascular
C. Cannon, V. Perkovic, R. Agarwal, J. Baldassarre, G. Bakris, D. Charytan, D. de Zeeuw, Robert Edwards, T. Greene, H. Heerspink, M. Jardine, A. Levin, Jingwei Li, B. Neal, C. Pollock, D. Wheeler, Hong Zhang, B. Zinman, K. Mahaffey   +18 more
semanticscholar   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source