Results 121 to 130 of about 416,102 (337)

Temporal glomerular gene expression dynamics during disease progression in a mouse model of hypertension‐accelerated diabetic kidney disease

Animal Models and Experimental Medicine, EarlyView.
The current study characterized temporal changes in glomerular gene expression, pathology, and biomarkers in a mouse model of hypertension‐accelerated diabetic kidney disease (DKD). Progressive albuminuria and glomerulosclerosis were paralleled by dynamic transcriptomic changes associated withmetabolic dysfunction, extracellular matrix remodeling, and ...
Adam B. Marstrand‐Jørgensen, Frederikke Emilie Sembach, Maria Ougaard, Ditte Hansen, Mette Viberg Østergaard, Henrik H. Hansen, Louise S. Dalbøge, Ole Jørgen Kaasbøll, Michael Christensen   +8 more
wiley   +1 more source

Synergistic Effects of Omeprazole and Metformin on Glycemic Control in Type 2 Diabetic Patients. A Randomized Clinical Study

Journal of the Dow University of Health Sciences, 2017
Objective: To evaluate the synergistic effects of omeprazole and metformin on glycemic control among patients with type 2 diabetes. Method: This randomized interventional clinical study was conducted in the Department of Pharmacology and ...
Fizzah Ali, Moosa Khan, Kausar Aamir, Muhammad Azhar Mughal   +3 more
doaj   +1 more source

Sleep and HbA1c in Patients With Type 2 Diabetes: Which Sleep Characteristics Matter Most?

Diabetes Care, 2019
OBJECTIVE Poor sleep has been identified as a risk factor for poor glycemic control in individuals with type 2 diabetes (T2D). As optimal sleep can be characterized in several ways, we evaluated which sleep characteristics are most strongly associated ...
A. Brouwer, Daniël H. van Raalte, F. Rutters, P. Elders, F. Snoek, A. Beekman, M. Bremmer   +6 more
semanticscholar   +1 more source

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles

Annals of Neurology, EarlyView.
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios, Jiali Gao, Carol A.C. Coupland, Julia Hippisley Cox, Martin R. Turner, Alexander G. Thompson   +5 more
wiley   +1 more source

Preventing misdiagnosis of diabetes in the elderly: age-dependent HbA1c reference intervals derived from two population-based study cohorts

BMC Endocrine Disorders, 2019
BackgroundMeasurement of gylcated hemoglobin A1c (HbA1c) plays a central role in monitoring quality of antidiabetic therapy and in the diagnosis of diabetes. Several studies report increased levels of HbA1c in nondiabetic elderly.
Annette Masuch, N. Friedrich, J. Roth, M. Nauck, U. Müller, A. Petersmann   +5 more
semanticscholar   +1 more source

Beyond right or wrong: How partial credit scoring on multiple‐choice questions improves student performance and assessment perceptions

British Journal of Clinical Pharmacology, EarlyView.
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid, Chris Armour, Katharina Brandl   +2 more
wiley   +1 more source

PRESENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS OF UNCONTROLLED AND CONTROLLED TYPE 2 DIABETES MELLITUS

Pakistan Armed Forces Medical Journal, 2019
Objectives: To determine the presence of non-alcoholic fatty liver disease in patients of uncontrolled and controlled type 2 diabetes mellitus. Study Design: Cross sectional study.
Aqeela Rashid, Sana Zafar, Aamir Bashir, Khush Bakht, Aman Ullah Bhalli   +4 more
doaj  

Prospective study of hyperglycemia and its impact on the causation of severe exacerbations in chronic obstructive pulmonary disease (COPD) patients attending a tertiary care hospital

Journal of Applied Pharmaceutical Research, 2023
Background: Hyperglycemic states are always associated with sudden onset of illnesses of both infectious and non-infectious nature. Chronic obstructive pulmonary disease is a chronic, lifelong suffering illness with sudden exacerbations.
doaj   +1 more source

Use and effectiveness of dapagliflozin in routine clinical practice. An Italian multicenter retrospective study [PDF]

, 2018
In randomized controlled trials (RCTs), sodium-glucose co-transporter-2 (SGLT2) inhibitors have been shown to confer glycaemic and extra-glycaemic benefits.
Avogaro A, Baldi I, Bottigliengo D, Consoli A, DARWIN-T2D network., Fadini GP, Giaccari A, Sesti G, Zatti G   +8 more
core   +1 more source

HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial [PDF]

, 2022
Anita Y. M. Kwan, Hertzel C. Gerstein, Jan Basile, Denis Xavier, Juan M. Maldonado, Sohini Raha, Маниге Кониг   +6 more
openalex   +1 more source