Results 141 to 150 of about 53,162 (283)

Adaptive Evolution and Distinct Mutation Signatures of Full‐Length HBV Quasispecies in HBeAg‐Negative Chronic Hepatitis B

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
HBeAg‐negative chronic hepatitis B harbors a highly heterogeneous HBV quasispecies shaped by region‐specific selection. Adaptive strategies underpinning viral persistence include: BCP/PreC mutations supporting replication, PreS/S mutations enabling immune evasion, and overlapping Pol/S mutations maintaining viral fitness.
Changhui Wu   +8 more
wiley   +1 more source

A case report: Complications of trans arterial embolization in managing ruptured hemorrhage of hepatocellular carcinoma

open access: yesMalignancy Spectrum, Volume 2, Issue 4, Page 204-208, December 2025.
TAE is an effective treatment for liver cancer rupture and bleeding. When treating patients with liver cancer rupture and bleeding, precise embolization is required during the TAE procedure to avoid extensive embolization. After liver cancer rupture and bleeding, a large amount of intra‐abdominal hemorrhage may induce complications such as hepatic ...
Gang Tong   +3 more
wiley   +1 more source

A Step‐by‐Step Workflow for Performing In Silico Clinical Trials With Nonlinear Mixed Effects Models

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 12, Page 1949-1964, December 2025.
ABSTRACT In silico clinical trials (ISCT) are computational frameworks that employ mathematical models to generate virtual patients and simulate their responses to new treatments, treatment regimens, or medical devices via simulations mirroring real‐world clinical trials.
Javiera Cortés‐Ríos   +4 more
wiley   +1 more source

Comparison between Lumipulse Presto HBsAg-HQ and iTACT-HBsAgin Chronic Hepatitis B with Seroclearance of HBsAg by Architect HBsAg QT

open access: diamond, 2021
Mariko Kobayashi   +12 more
openalex   +2 more sources

Long‐Term Outcomes of Patients Who Receive a Liver Transplant for Hepatitis B With Limited Use of Hepatitis B Immunoglobulin

open access: yesClinical Transplantation, Volume 39, Issue 12, December 2025.
ABSTRACT Chronic hepatitis B virus (HBV) infection is a leading cause of cirrhosis and hepatocellular carcinoma (HCC). Post‐transplant HBV reinfection represents an important post‐liver transplantation (LT) complication, which can result in death or graft loss.
Giovanni A. Roldan   +3 more
wiley   +1 more source

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