Results 141 to 150 of about 93,843 (327)

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 30, August 14, 2025.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang, Yan Guo, Wen‐Jing Yuan, Yu‐Man Chen, Bo‐Wei Liu, Wen‐Tao Li, Xiang‐Ming Ding, Xu‐Dong Fu, Yu‐Han Lou, Zhuo‐Ran Chen, Xiao‐Ying Luo, Song‐Ze Ding, Bing‐Yong Zhang, Xiu‐Ling Li, Yong‐Zhi Hong, Shun‐Dong Cang, Dong‐Xiao Li, Ling Lan   +17 more
wiley   +1 more source

Biologic significance of the detection of HBsAg and HBcAg in liver and tumor from 204 HBsAg-positive patients with primary hepatocellular carcinoma [PDF]

, 1989
Hey‐Chi Hsu, Tsung‐Teh Wu, Jin‐Chuan Sheu, Chieng-Yen Wu, Tzyy‐Jen Chiou, Chu-Shue Lee, Ding‐Shinn Chen   +6 more
openalex   +1 more source

Anti‐Angiogenic Agents for Advanced Hepatocellular Carcinoma Induce Liver Atrophy

Cancer Medicine, Volume 14, Issue 15, August 2025.
ABSTRACT Aim Systemic therapy for advanced hepatocellular carcinoma (HCC) includes multi‐kinase inhibitors with anti‐vascular endothelial growth factor (VEGF) activity and anti‐VEGF monoclonal antibodies in combination with immune checkpoint inhibitors.
Taijiro Wake, Tomoharu Yamada, Ryosuke Tateishi, Makoto Moriyama, Yuki Matsushita, Kazuya Okushin, Takuma Nakatsuka, Masaya Sato, Tatsuya Minami, Yotaro Kudo, Mitsuhiro Fujishiro   +10 more
wiley   +1 more source

The Levels of Serum HBV Pre-Genomic RNA and Its Associated Factors Among HBV-Infected Patients: A Retrospective Cohort Study in Hangzhou, Zhejiang, China

International Journal of General Medicine
Zhongbao Zuo,1,* Jing Wu,1,* Miaochan Wang,1 Rui Wu,2 Xiaojing Zhang,2 Lanlan Hu,1 Huaizhong Cui,1 Ting Feng,3 Aifang Xu,1 Shourong Liu2 1Department of Clinical Laboratory, Hangzhou Xixi Hospital, Zhejiang, 310023, People’s Republic of China ...
Zuo Z, Wu J, Wang M, Wu R, Zhang X, Hu L, Cui H, Feng T, Xu A, Liu S   +9 more
doaj  

Morphological expression of cellular immunity against HBsAg in hepatitis B

, 1976
Toshio Shikata, Tsutomu Karasawa, T Uzawa, Makoto Kako, Masao Torii, Hiroshi Suzuki   +5 more
openalex   +2 more sources

A Case of Combined Hepatocellular‐Cholangiocarcinoma Diagnosis and Treatment With Literature Review

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT This report presents a rare case of a 43‐year‐old man with unresectable combined hepatocellular‐cholangiocarcinoma who, after undergoing transarterial chemoembolization, systemic chemotherapy, and stereotactic body radiation therapy, accepted curative resection and obtained an overall survival of 25 months to date. The case highlights the need
Xuliang Chen, Hengkai Zhu, Liyan Tao, Shusen Zheng, Hua Guo   +4 more
wiley   +1 more source

Hepatitis B Virus DNA in Serum of Pregnant Women with HBsAg and HBeAg or Antibodies to HBe [PDF]

, 1984
R. A. Heijtink, Piet J. Boender, Solko W. Schalm, N. Masurel   +3 more
openalex   +1 more source

Toxin‐Induced Liver Injury Following Bear Bile Consumption in a Middle‐Aged Female in Bhutan: A Case Report

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Consumption of bear bile can cause severe hepatotoxicity. Clinicians should consider toxin‐mediated liver injury in patients with unexplained jaundice. Early recognition, discontinuation of the offending agent, and potential use of N‐acetylcysteine and ursodeoxycholic acid may aid recovery.
Sonam Wangzin Rabjay, Thai Wangmo, Thinley Dorji   +2 more
wiley   +1 more source

Significance of Serum and Hepatic Markers of Hepatitis B Viral Infection in Hbsag–Positive and Hbsag–Negative Chronic Active Hepatitis [PDF]

, 1985
John Freiman, Robert P. Eckstein, Geoffrey W. McCaughan, C. Parsons, Stuart J. Davies, Peter S. Diegutis, Leslie Burnett, N. D. Gallagher   +7 more
openalex   +1 more source

A Rare Case of Lichen Planus/Discoid Lupus Erythematosus Overlap Syndrome and Its Successful Treatment

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT An uncommon condition referred to as the overlap syndrome of lichen planus (LP) and lupus erythematosus (LE) exhibits immunopathological, histological, and clinical characteristics of both LP and LE. Though LP and LE are common individually, their overlap is rare.
Shehdev Meghwar, Muskan Batra, Noor Zehra Shabbir, Preety Devi, Ajeet Singh, Asma Ikram, Amogh Verma   +6 more
wiley   +1 more source