Results 11 to 20 of about 93,843 (327)

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

IL-10 Promoter Polymorphism Distribution among HBsAg-Reactive and HBsAg-Nonreactive Blood Donors

Majalah Kedokteran Bandung, 2020
Hepatitis B surface antigen (HBsAg) serves as a serological marker for Hepatitis B virus (HBV) infection. People with HBV asymptomatic infection might readily donate blood due to the lack of clinical manifestations.
Rahmat Azhari Kemal, Arfianti Arfianti, Reni Oktora, Bebe Gani, Fauzia Andrini Djojosugito, Winarto Winarto   +5 more
doaj   +1 more source

Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients

Scientific Reports, 2020
Chronic hepatitis B (CHB) infection functional cure is defined as sustained loss of HBsAg and several therapeutic strategies are in clinical development designed to pharmacologically reduce serum HBsAg, break immune tolerance, and increase functional ...
Jin Hyang Kim, Alip Ghosh, Natarajan Ayithan, S. Romani, A. Khanam, Jang-June Park, R. Rijnbrand, Lydia Tang, M. Sofia, S. Kottilil, Chris B. Moore, B. Poonia   +11 more
semanticscholar   +1 more source

Distribution of ABO, Rhesus Blood Groups, Transfusion Transmitted Diseases and Adverse Donor Reactions in a Blood Bank of a Tertiary Care Hospital: A Five Year Study [PDF]

National Journal of Laboratory Medicine, 2016
Introduction: Study of the distribution of A, B, O blood group systems is essential for genetic studies, medico – legal issues and importantly for efficient delivery of blood bank services. Also important is the immunologic safety of the donated blood
Lekha Mandodar, Archana Shetty, Vijaya Chowdappa   +2 more
doaj   +1 more source

Factors Associated With Rates of HBsAg Seroclearance in Adults With Chronic HBV Infection: A Systematic Review and Meta-analysis.

Gastroenterology, 2019
BACKGROUND & AIMS Seroclearance of hepatitis B surface antigen (HBsAg) is a marker for clearance of chronic hepatitis B virus (HBV) infection, but reported annual incidence rates of HBsAg seroclearance vary.
Y. Yeo, H. Ho, Hwai I. Yang, T. Tseng, T. Hosaka, H. Trinh, Min-Sun Kwak, Young Min Park, J. Fung, M. Buti, Manuel Rodríguez, S. Treeprasertsuk, C. Preda, T. Ungtrakul, P. Charatcharoenwitthaya, Xiangyong Li, Jiayi Li, Jian Q. Zhang, M. Le, Bin Wei, B. Zou, A. Le, Donghak Jeong, Nicholas Chien, Leslie Y. Kam, Chiao-Chin Lee, M. Riveiro‐Barciela, D. Istratescu, T. Sriprayoon, Y. Chong, T. Tanwandee, M. Kobayashi, F. Suzuki, M. Yuen, Hyo‐suk Lee, J. Kao, A. Lok, Chun-Ying Wu, M. Nguyen   +38 more
semanticscholar   +1 more source

Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg

Scientific Reports, 2020
Hepatitis D virus (HDV) requires hepatitis B surface antigen (HBsAg) for its assembly and release. Current HBV treatments are only marginally effective against HDV because they fail to inhibit HBsAg production/secretion.
L. Shekhtman, S. Cotler, L. Hershkovich, S. Uprichard, M. Bazinet, V. Pantea, V. Cebotarescu, Lilia Cojuhari, P. Jimbei, A. Krawczyk, U. Dittmer, A. Vaillant, H. Dahari   +12 more
semanticscholar   +1 more source

Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance We detected cfDNA somatic mutations in combination with protein markers to efficiently identify early stage HCC from asymptomatic HBsAg-seropositive individuals in a community population.
C. Qu, Yuting Wang, Pei-pei Wang, Kun-Tian Chen, Min-jie Wang, H. Zeng, Jianquan Lu, Q. Song, B. Diplas, D. Tan, C. Fan, Q. Guo, Zheng Zhu, H. Yin, Liping Jiang, Xixi Chen, Hui Zhao, Huan He, Yong Wang, Guangyu Li, X. Bi, Xinming Zhao, Tao-yang Chen, Hongping Tang, Chuanguo Lv, Dongmei Wang, Wanqing Chen, Jianguo Zhou, Hong Zhao, Jianqiang Cai, Xiaoyue Wang, Sizhen Wang, Hai Yan, Y. Zeng, W. Cavenee, Y. Jiao   +35 more
semanticscholar   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Prevalence of transfusion transmitted infection among blood donors in Jigawa state, Nigeria [PDF]

Microbes and Infectious Diseases, 2023
Aim: The study was designed to determine seroprevalence of Transfusion transmissible diseases (TTD) among blood donors attending general hospitals in Jigawa Nigeria. Methods: Four hundred blood donors were screened for Malaria parasite, Hepatitis B viral
Bello Garba, USMAN ADAMU, ISMAIL AHMED, DAN LARAI FAGWALAWA   +3 more
doaj   +1 more source

Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice

Nature Communications, 2019
Hepatitis B virus (HBV) can induce chronic inflammation, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite evidence suggesting a link between adaptive immunity and HBV-related diseases in humans, the immunopathogenic mechanisms involved ...
Lu Zong, Hui Peng, Cheng-song Sun, Fenglei Li, M. Zheng, Yongyan Chen, Haiming Wei, R. Sun, Z. Tian   +8 more
semanticscholar   +1 more source