Results 41 to 50 of about 132,691 (312)

Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg

Scientific Reports, 2020
Hepatitis D virus (HDV) requires hepatitis B surface antigen (HBsAg) for its assembly and release. Current HBV treatments are only marginally effective against HDV because they fail to inhibit HBsAg production/secretion.
L. Shekhtman, S. Cotler, L. Hershkovich, S. Uprichard, M. Bazinet, V. Pantea, V. Cebotarescu, Lilia Cojuhari, P. Jimbei, A. Krawczyk, U. Dittmer, A. Vaillant, H. Dahari   +12 more
semanticscholar   +1 more source

Potential mutations associated with occult hepatitis B virus status [PDF]

, 2014
Context: Occult hepatitis B virus (HBV) status (OHBS) is simply defined as the presence of HBV DNA in the liver (with or without detectable HBV DNA in the serum), in the absence of serum HBV surface antigen (HBsAg). Importance of OHBS is mostly clinical,
Besharat, S., Katoonizadeh, A., Moradi, A.   +2 more
core   +1 more source

Hepatitis B elimination in children of Slovenian origin born in Slovenia after the introduction of preventive strategies: The results of a national study

Slovenian Journal of Public Health, 2022
In Slovenia national strategies to prevent hepatitis B virus (HBV) infection in children were introduced in the mid-nineties. The aim of the present study was to analyze the epidemiological characteristics of chronic hepatitis B infection in children in ...
Kmet Nina Grasselli, Poljak Mario, Zakotnik Breda, Matičič Mojca   +3 more
doaj   +1 more source

The Roles of Alix and VPS4A in Autophagy and Endosomal Pathways and Their Relation to HBV Replication. [PDF]

FASEB J
Alix and VPS4A function in HBV biogenesis and degradation in the context of the endosomal and autophagic pathways. Alix and VPS4A orchestrate HBV secretion and degradation via endosomal and autophagic pathways. Under normal conditions, ESCRT ensures efficient virion budding and MVB formation.
Li J, Kemper T, Tong S, Wang X, Lin Y, Lu M.   +5 more
europepmc   +2 more sources

Reactivation of hepatitis B virus with immune-escape mutations after ocrelizumab treatment for multiple sclerosis [PDF]

, 2019
Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) that is closely related to rituximab. We describe a case of hepatitis B virus (HBV) reactivation in an MS patient with resolved HBV infection receiving ...
Altieri, Marta, Annecca, Rosanna, Aragri, Marianna, Ciardi, Maria R, Iannetta, Marco, Mastroianni, Claudio M, Pontecorvo, Simona, Russo, Gianluca, Salpini, Romina, Svicher, Valentina, Vullo, Vincenzo, Zingaropoli, Maria A   +11 more
core   +1 more source

Seroprevalence of Hepatitis B Virus in HIV Tested Positive Patients Accessing Treatment in Specialist Hospital Jimeta

Dr. Sulaiman Al Habib Medical Journal, 2021
Background: Human Immunodeficiency Virus (HIV) positive patients are likely to be at risk of other infectious pathogens such as Hepatitis B Virus (HBV).
Mohammed Bashir, Halima Ibrahim, Halima Isa   +2 more
doaj   +1 more source

Evidence for the stress-linked immunocompetence handicap hypothesis in humans [PDF]

, 2012
Secondary sexual traits that develop under the action of testosterone, such as masculine human male facial characteristics, have been proposed to signal the strength of the immune system due to the sex hormone's immunosuppressive action.
Kecko, Sanita, Kivleniece, Inese, Krama, Tatjana, Krams, Indrikis, Moore, Fhionna R., Rantala, Markus J., Skrinda, Ilona   +6 more
core   +4 more sources

Immunogenicity of a two-dose investigational hepatitis B vaccine, HBsAg-1018, using a toll-like receptor 9 agonist adjuvant compared with a licensed hepatitis B vaccine in adults.

Vaccine, 2018
BACKGROUND Hepatitis B virus infection remains an important public health problem in the United States. Currently approved alum-adjuvanted vaccines require three doses and have reduced immunogenicity in adults, particularly in those who have diabetes ...
S. Jackson, J. Lentino, James Kopp, Linda Murray, W. Ellison, Margaret Rhee, G. Shockey, L. Akella, Kimberly Erby, W. Heyward, R. Janssen   +10 more
semanticscholar   +1 more source

Health of Special Immigrant Visa holders from Iraq and Afghanistan after arrival into the United States using Domestic Medical Examination data, 2014-2016: A cross-sectional analysis. [PDF]

, 2020
BACKGROUND: Since 2008, the United States has issued between 2,000 and 19,000 Special Immigrant Visas (SIV) annually, with the majority issued to applicants from Iraq and Afghanistan.
Aguirre, Jenny, Cabanting, Nuny, Ford, Rebecca, Hughes, Stephen, Jentes, Emily S, Kawasaki, Breanna, Kennedy, Lori, Kumar, Gayathri S, Mamo, Blain, Montour, Jessica, Payton, Colleen, Pezzi, Clelia, Scott, Kevin, Titus, Melissa, Urban, Kailey, Wien, Simone   +15 more
core   +2 more sources

Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice

Nature Communications, 2019
Hepatitis B virus (HBV) can induce chronic inflammation, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite evidence suggesting a link between adaptive immunity and HBV-related diseases in humans, the immunopathogenic mechanisms involved ...
Lu Zong, Hui Peng, Cheng-song Sun, Fenglei Li, M. Zheng, Yongyan Chen, Haiming Wei, R. Sun, Z. Tian   +8 more
semanticscholar   +1 more source