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Post-treatment HBsAg decline predicts high rate of HBsAg loss after stopping entecavir or tenofovir in HBeAg-negative patients without retreatment

Digestive and Liver Disease, 2023
Little is known about the role of post-treatment HBsAg decline in HBsAg loss following nucleos(t)ide analogues cessation.HBeAg-negative patients without cirrhosis who previously received entecavir or tenofovir disoproxil fumarate (TDF) were enrolled (n=530).
Hsin-Wei Fang   +5 more
openaire   +2 more sources

Baseline HBsAg levels associated with HBsAg loss in HBeAg-negative chronic hepatitis B infection with persistently normal alanine aminotransferase

Clinics and Research in Hepatology and Gastroenterology, 2019
We aimed to assess the long-term outcomes of e antigen-negative chronic hepatitis B (CHB) infection with low hepatitis B virus (HBV) DNA level (
Li, Chen   +5 more
openaire   +2 more sources

Loss of HBsAg with interferon‐α therapy in chronic hepatitis D virus infection

Journal of Medical Virology, 1993
Eleven patients with chronic hepatitis D virus (HDV) infection who had chronic active hepatitis and HDV antigen on liver biopsy were randomised in a crossover therapeutic trial of interferon-alpha 2b vs. no therapy. Nine patients had a history of intravenous drug use (drug free > 6 months before therapy), 8 had histological evidence of cirrhosis, and 7
J Y, Lau   +7 more
openaire   +2 more sources

Abdominal pain and weight loss in an HBsAg positive 56-year-old Afghan woman

Journal of Clinical Virology, 2011
A 56-year-old Afghan woman presented with the complaints f abdominal pain, anorexia and significant weight loss since 2 onths ago. She was a known case of hepatitis B infection for ears with no further follow-up, who had received no therapy or this infection. On examination, she had a 38.4 ◦C oral temerature but the other vital signs were in the normal
Naderi, H. R., Yarani, M., Sheybani, F.
openaire   +2 more sources

HBcrAg, pg RNA and HBsAg dynamically supervise the seroconversion of HBsAg with anti-viral therapy: "Loss of HBsAg" maybe not a good end-point of anti-viral therapy.

Clinica chimica acta; international journal of clinical chemistry, 2020
We aimed to identify predictor of HBsAg seroconversion using serum quantitative pg-RNA, HBcrAg and HBsAg in CHB patients with anti-viral therapy.A total of 335 patients with anti-viral therapy between 2013 and 2017 were enrolled, only 23 achieved the seroconversion of HBsAg, other 138 patients without seroconversion of HBsAg were selected randomly in ...
Guanghua, Ma   +6 more
openaire   +1 more source

Loss of HBsAg after interferon-α treatment: Cure of chronic hepatitis B virus?

Hepatology, 1991
Sixty-four patients with chronic hepatitis B who were treated with interferon-α (recombinant IFN-α-2a in 9 patients, recombinant IFN-α-2b in 50 patients and lymphoblastoid IFN-α-n1 in 5 patients) in protocols conducted at the Liver Diseases Section of the National Institutes of Health between 1984 and 1986 were observed with ...
openaire   +2 more sources

Quantification of HBsAg (HBsAg-Q) in HBeAg-Negative Patients Receiving Nucleos(T)ide Analogues to Predict the Loss of HBsAg

Journal of Hepatology, 2016
T. Broquetas   +11 more
openaire   +1 more source

Deletions in the HBV s gene are associated with altered HBsAg composition in patients with HBsAg loss during NA therapy

Zeitschrift für Gastroenterologie, 2021
M Pfefferkorn   +4 more
openaire   +1 more source

Kinetics of Hbsag Loss in Nucleoside Analogue and Interferon Therapies

Gastroenterology, 2017
Daniel Suarez   +6 more
openaire   +1 more source

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