Results 91 to 100 of about 113,181 (243)

Microbial metabolites in tumor epigenetic regulation

iMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Mutations in the Basal Core Promoter and Precore/Core Regions of Hepatitis B Virus in Patients Co-Infected With Human Immunodeficiency Virus

Medical Laboratory Journal, 2016
Background and objectives: Globally, about one third of the population has been infected with Hepatitis B virus (HBV) and more than 400 million people have become chronically infected. Nearly, 20-25% of all carriers develop serious liver diseases such as
Ahmad Hosseinzadeh Adli, Chiman Karami, Sareh Zhand, Reza Talei, Abdolvahab Moradi   +4 more
doaj  

Ensemble rainfall–runoff modeling of physically based semi-distributed models using multi-source rainfall data fusion

Journal of Water and Climate Change
This study was aimed at ensemble rainfall–runoff modeling by Soil and Water Analysis Tool (SWAT), the Hydrologic Engineering Center's Hydraulic Modeling System, and Hydrologiska Byråns Vattenbalansavdelning of Gilgel-Abay watershed, Blue Nile basin ...
Tagesse Gichamo, Vahid Nourani, Hüseyin Gökçekuş, Gebre Gelete   +3 more
doaj   +1 more source

Epidemiology and Challenges of HBV/HIV Co-Infection Amongst HIV-Infected Patients in Endemic Areas: Review

HIV/AIDS: Research and Palliative Care, 2021
Letebrhan Weldemhret Medical Microbiology, Tigray Health Research Institute, Mekelle, EthiopiaCorrespondence: Letebrhan Weldemhret Email Letinaweldemhret@gmail.comAbstract: With the introduction of highly active antiretroviral treatment, HIV-related ...
Weldemhret L
doaj  

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

iNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu, Lin Tang, Hongyan Li, Hao Li, Jiamei Wang   +4 more
wiley   +1 more source

Seropositivity and coinfection of hepatitis B and hepatitis C viruses in Central India: A hospital-based study

Journal of Family Medicine and Primary Care
Background Hepatitis B virus (HBV) and Hepatitis C virus (HCV) show similarity in the transmission, distribution, hepatotropism, and leading to chronic asymptomatic infection.
Rajeev K. Jain, Rakesh Shrivastava, Shailendra K. Jain, Deepti Chaurasia, Anamika Jain, Swati Jain, Kamlesh K. Ahirwar, Nagaraj Perumal   +7 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

A Study on the Characteristics of Sonazoid Contrast‐Enhanced Ultrasound in the Transitional Phase for Common Focal Liver Lesions and Its Value in Differential Diagnosis

Journal of Ultrasound in Medicine, EarlyView.
Objective To investigate the value of transitional phase characteristics on Sonazoid contrast‐enhanced ultrasound (S‐CEUS) in the differential diagnosis of common focal liver lesions (FLLs). Materials and Methods This prospective multicenter study enrolled 122 participants with FLLs from 8 medical centers between December 2023 and March 2025. The study
Yunhao Luo, Danlin Wen, Jing Zhang, Zhengrong Song, Yang Liu, Yan Liu, Qiang Mao, Yunquan Zhou, Liwen Ma, Congcong Yu, Lang Qiao   +10 more
wiley   +1 more source

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin, Ming‐Lun Yeh, Po‐Cheng Liang, Shinn‐Cherng Chen, Chung‐Feng Huang, Jee‐Fu Huang, Chia‐Yen Dai, Ming‐Lung Yu, Wan‐Long Chuang   +8 more
wiley   +1 more source