Results 81 to 90 of about 155,598 (315)

HBV-independent interaction between YTHDF2 proteins with ISG20.

, 2020
(A) FLAG-YTHDF2 and HA-ISG20D94G plasmids were co-transfected into HepG2 cells. After 48h of incubation cells were harvested and lysates were prepared. FLAG antibody was used for IP and then probed with FLAG and HA antibody after Western Blot.
Saiful Anam Mir (8452383), Mohsin Khan (352381), Hasan Imam (8452380), Aleem Siddiqui (395750), Geon-Woo Kim (845115)   +4 more
core   +1 more source

HBV Immunomics 10X and Smart-seq2 integrated data

, 2023
<p>Here, we established a single-cell RNA-sequencing (scRNA-seq) dataset of HBV immune responses in patients to contribute to a better understanding of the dysregulated immune response in CHB.
François Habersetzer, Thomas F. Baumert, Tobias Nilsson, Nadege Pelletier, Antonio Saviano, Marianne Forkel, Tony Kam-Thong, Klas Hatje, Nadine Kumpesa, Pauline Simo-Noumbissie, Nicolas Giroud   +10 more
core   +1 more source

HBV replication inhibitors

Antiviral Research, 2020
Chronic Hepatitis B Virus infections afflict >250 million people and kill nearly 1 million annually. Current non-curative therapies are dominated by nucleos(t)ide analogs (NAs) that profoundly but incompletely suppress DNA synthesis by the viral reverse transcriptase. Residual HBV replication during NA therapy contributes to maintenance of the critical
Claire Pierra Rouviere, Cyril B. Dousson, John E. Tavis   +2 more
openaire   +3 more sources

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Assessment of the Prevalence of Markers of Monoinfection with Hepatitis C Virus and Coinfection with Hepatitis C and B Viruses among the Personnel of Medical Institutions of an Endemic Region

Эпидемиология и вакцинопрофилактика
Relevance. Parenteral viral hepatitis B (HBV) and C (HCV) affect not only millions of people, but also healthcare workers due to professional contacts, which lead to the progression of liver pathology and a reduction in medical activity. Numerous studies
M. P. Kostinov, N. A. Magomedova, I. A. Khrapunova, A. V. Linok, E. Yu. Malinnikova, G. I. Alatortseva, L. N. Pritvorova, L. N. Nesterenko, I. I. Amiantova, V. V. Dotsenko, V. Yu. Kabargina, V. B. Polishchuk, M. N. Loktionova, A. A. Besshaposhnikova   +13 more
doaj   +1 more source

Assisted Reproductive Technology and Obstetric Outcome in Couples when The Male Partner Has A Chronic Viral Disease [PDF]

International Journal of Fertility and Sterility, 2014
Background: Assisted reproductive technology (ART) with washed semen can achieve pregnancy with minimal risk of horizontal and vertical transmission of chronic viral diseases (CVD) such as human immunodeficiency virus (HIV), hepati- tis C virus (HCV ...
Irene Molina, María Carmen del Gonzalvo, Ana Clavero, Miguel Ángel López-Ruz, Juan Mozas, Juan Pasquau, Antonio Sampedro, Luis Martínez, José Antonio Castilla   +8 more
doaj  

PrEP at the site of action in cisgender and transgender women: A pharmacology study of blood and rectal CD4+ lymphocytes

British Journal of Clinical Pharmacology, EarlyView.
Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie, Megha Srivasta, Edward R. Cachay, Leah Burke, Sara Gianella, Stephen Rawlings, Frank Z. Stanczyk, Craig Sykes, Angela D. M. Kashuba, Jill Blumenthal, Mackenzie L. Cottrell   +10 more
wiley   +1 more source

Twenty nail onychomadesis following acute viral hepatitis B infection

Journal of Marine Medical Society, 2020
Onychomadesis is a nail plate abnormality with temporary cessation in the growth of the nail plate due to disturbances in the nail matrix. Any local or systemic condition affecting the nail matrix directly or indirectly can lead to onychomadesis.
M Sivasankari, Preema Sinha
doaj   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, EarlyView.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

Serum Lactate Level Predicts Short-Term and Long-Term Mortality of HBV-ACLF Patients: A Prospective Study

Therapeutics and Clinical Risk Management, 2020
Yuan Nie,* Yue Zhang,* Lin-xiang Liu, Xuan Zhu Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuan ...
Nie Y, Zhang Y, Liu L, Zhu X
doaj