Results 111 to 120 of about 342,150 (384)
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
Advanced Science, EarlyView.This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
3.5Å cryoEM structure of hepatitis B virus core assembled from full-length core protein. [PDF]
, 2013 The capsid shell of infectious hepatitis B virus (HBV) is composed of 240 copies of a single protein called HBV core antigen (HBc). An atomic model of a core assembled from truncated HBc was determined previously by X-ray crystallography.
Jih, Jonathan +4 more
core
Hepatitis B among Pacific Islanders in Southern California: how is health information associated with screening and vaccination? [PDF]
, 2010 We measured Hepatitis B virus (HBV) transmission knowledge and self-reported screening/testing behavior among Pacific Islanders (Guamanians/Chamorros, Samoans, and Tongans) in Southern California. We also examined access and trust by Pacific Islanders of
Anna J. Kim +12 more
core +3 more sources
PLoS ONE, 2017 The structural maintenance of chromosome 5/6 complex (Smc5/6) is a restriction factor that represses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing HBV X protein (HBx), which targets Smc5/6 for degradation.
C. Niu +14 more
semanticscholar +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Advanced Medical JournalBackground & objectives: Hemodialysis patients are susceptible to various types of infections, such as exposure to blood borne pathogens. This study aims to identify the effects of training on the incidence of nosocomial viral hepatitis B & C infection ...
Qasim Burhan Abdullah +2 more
doaj +1 more source
The Pan African Medical Journal, 2018 INTRODUCTION: In Burundi, blood safety is one of the concerns of the Ministry of Public Health and Fight against AIDS. To this end, all donor blood bags must be screened for hepatitis B and C, that is the reason why the National Blood Transfusion Center (
René Kwizera +3 more
doaj +1 more source
Honour based violence and the multi-agency approach in Nottingham: response of local agencies to honour based violence [PDF]
, 2011 The focus of the research was to gain an understanding of the current levels of HBV in Nottingham and the nature of the multi-agency response. The main aim of the research was to gain an understanding of practitioners' work with a range of issues ...
Gillespie, T +2 more
core
Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Nature Communications, 2016 Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration detection and RNA sequencing, we identify 4,225 HBV integration events in ...
Ling-hao Zhao +40 more
semanticscholar +1 more source
Advanced Science, EarlyView.In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen +15 more
wiley +1 more source