Results 301 to 310 of about 333,660 (389)

Rechallenge of Atezolizumab Plus Bevacizumab Therapy in Patients With Unresectable Hepatocellular Carcinoma

Hepatology Research, EarlyView.
ABSTRACT Background Atezolizumab plus bevacizumab (AB) is a standard first‐line therapy for unresectable hepatocellular carcinoma (HCC). However, data on the efficacy and safety of AB rechallenge (re‐AB) after discontinuation are limited. Methods We conducted a retrospective analysis of 13 patients with unresectable HCC who received initial AB ...
Yuichiro Suzuki, Teiji Kuzuya, Leona Osawa, Yasuyuki Komiyama, Hitomi Takada, Shuya Matsuda, Masaru Muraoka, Mitsuaki Sato, Shinya Maekawa, Nobuyuki Enomoto, Hisanori Muto, Yoshihiko Tachi, Yoshiki Hirooka, Atsunori Tsuchiya   +13 more
wiley   +1 more source

Highly stable Cas9 promotes HBV genome destruction by antagonizing HSC70-mediated degradation. [PDF]

Emerg Microbes Infect
Li Z, Song Y, Huang H, Chen R, Liu M, Yang X, Luo Z, Liu BM, Wang J.   +8 more
europepmc   +1 more source

Towards an HBV cure: state-of-the-art and unresolved questions—report of the ANRS workshop on HBV cure

Gut, 2015
M. Zeisel, J. Lucifora, W. Mason, C. Sureau, J. Beck, M. Levrero, M. Kann, P. Knolle, M. Benkirane, D. Durantel, M. Michel, B. Autran, F. Cosset, H. Strick-Marchand, C. Trépo, J. Kao, F. Carrat, K. Lacombe, R. Schinazi, F. Barré-Sinoussi, J. Delfraissy, F. Zoulim   +21 more
semanticscholar   +1 more source

Fibulin Family Members: New Players in Liver Fibrosis and Potential Biomarkers in Chronic Liver Diseases

Hepatology Research, EarlyView.
ABSTRACT Chronic liver diseases (CLD) arising from various etiologies including viral hepatitis, excessive alcohol intake, alcoholic associated liver disease (ALD) and metabolic dysfunction‐associated steatotic liver disease (MASLD), are associated with persistent hepatic injury ultimately resulting in fibrosis.
Fidaa Bouezzedine, Célia Thomas, Nathalie Théret   +2 more
wiley   +1 more source

Accurate and Cost-Efficient Whole Genome Sequencing of Hepatitis B Virus Using Nanopore. [PDF]

J Med Virol
Stenbäck JB, Schmidt D, Noborg U, Gustafsson J, Norberg P, Andersson ME, Fu MX, Harvala H, Ringlander J.   +8 more
europepmc   +1 more source

Mutations of Glucocorticoid Responsive Element of HBV DNA.

, 1998
Hiroshi Suzuki, Michio Sata, Masaru Sasaki, Shirou Murashima, Fuyuhiko Akiyoshi, Seiji Noguchi, Kyuichi Tanikawa   +6 more
openalex   +2 more sources

Employment Status of Patients With Liver Disease: A Nationwide Questionnaire Survey in Japan

Hepatology Research, EarlyView.
In our nationwide survey, analyzing over 2000 patients, those with viral hepatitis were less likely to disclose their condition, and overall awareness of support programs remained limited. These findings highlight the need to promote support for balancing treatment and work more actively, particularly in small‐ and medium‐sized workplaces.
Yoshio Tokumoto, Yoichi Hiasa, Yoshihito Uchida, Takashi Oono, Atsushi Yukimoto, Takao Watanabe, Ryo Sasaki, Sachiko Tatsuki, Hironori Tanaka, Takako Inoue, Mika Horino, Akira Hirose, Tadashi Ikegami, Jun Inoue, Hiroshi Isoda, Hirokazu Takahashi, Yoshihisa Arao, Isao Hidaka, Hiroki Tojima, Satoru Kakizaki, Tetsuro Shimakami, Masayuki Tatemichi, Tatehiro Kagawa, Koji Ogawa, Masatsugu Ohara, Ritsuzo Kozuka, Masaru Enomoto, Mizuki Endo, Yuichiro Eguchi, Kenji Nagata, Masaaki Korenaga   +30 more
wiley   +1 more source

HBV-encoded circRNA-5 promotes hepatocellular carcinoma progression by regulating the miR-9-3p/Hippo signaling axis. [PDF]

Microbiol Spectr
Yang Y, Shen Y, Dang Y, Huang J, Su Y, Zhang J, Jiang X, Luo X, Wang J, Liu J.   +9 more
europepmc   +1 more source

Efficacy and Safety of Hypofractionated Radiation Therapy Combined With Immunotherapy for Hepatocellular Carcinoma With Vp4 Portal Vein Tumor Thrombosis

Hepatology Research, EarlyView.
ABSTRACT Background Hepatocellular carcinoma (HCC) with Vp4 portal vein tumor thrombosis (PVTT) has an extremely poor prognosis, and evidence for effective systemic therapy is limited. Preclinical studies suggest that hypofractionated radiation therapy (HFRT) may enhance immune checkpoint inhibitor (ICI) efficacy through immunogenic cell death and ...
Masahiko Tameda, Hideaki Tanaka, Yutaka Toyomasu, Mizuki Kawachi, Hirono Owa, Mone Tsukimoto, Yasuyuki Tamai, Naoto Fujiwara, Ryuta Shigefuku, Suguru Ogura, Yoshihito Nomoto, Hayato Nakagawa   +11 more
wiley   +1 more source

U-Shaped Relationship Between CT-Measured Liver-To-Spleen Volume Ratio and Mortality in HBV-ACLF Patients. [PDF]

J Viral Hepat
Yan L, Yuan M, Su M, Cui K, Teng X, Yuan F, Bai L.   +6 more
europepmc   +1 more source