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Results 71 to 80 of about 87,798 (290)

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila +12 more
wiley +1 more source

An introduction to ethical theory for healthcare assistants [PDF]

, 2017
This article will explore and summarise the four main ethical theories that have relevance for healthcare assistants. These are utilitarianism, deontology, virtue ethics, and principlism.
Blackshaw, Bruce P., Rodger, Daniel
core +1 more source

Higher complement C4 gene copy number constitutes a shared genetic risk factor for giant cell arteritis and IgA vasculitis

Arthritis &Rheumatology, Accepted Article.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +296 more
wiley +1 more source

Comparison of Some Parts of Cotoneaster coriaceus Franch. Plant in Terms of Phytochemicals and Antioxidant Capacity

Turkish Journal of Agriculture: Food Science and Technology
Cotoneaster spp. is a plant belonging to the Rosaceae family, which includes different genera and taxa. It is a woody plant that grows from shrubs to trees depending on its height (between 0.2-20 m) and grows in the temperate areas of Europe, North ...
Hatice Feyza Akbulut
doaj +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi +11 more
wiley +1 more source

Financial Toxicity Associated with Biological Medicines: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka +4 more
wiley +1 more source

Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis: A shared phenotype across brain‐expressed sodium channelopathies

Epilepsia, EarlyView.
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli +43 more
wiley +1 more source

Applications of Synthetic Hybrid-Scale Fiber Matrix in Head and Neck Reconstruction: A Case Series

Case Reports in Oncology
Introduction: Patients with head and neck cancer often necessitate complex reconstructions, considering both functional and esthetic concerns. Reconstructions are further complicated by previous radiation therapy and patient co-morbidities, which impair ...
Peter Horwich +3 more
doaj +1 more source

Essential Training for an Essential Role: Dietitians and Eating Disorder Care

European Eating Disorders Review, EarlyView.
ABSTRACT Aims Dietitians are critical members of the multidisciplinary eating disorder treatment team. Dietitians frequently encounter clients with undiagnosed or undisclosed eating disorders; however, many graduate dietitians lack specialised eating disorder training. This study evaluates the effectiveness of the Dietitian Essentials eLearning program
Caroline A. Hill +5 more
wiley +1 more source

Experimental Investigation of Sensitivity for Coal and Gas Outburst Risk Prediction Indexes in Raw and Tectonic Composite Coal Seams

Energy Science &Engineering, EarlyView.
A comparative study was conducted on gas desorption laws of raw and tectonic coals. The sensitivity of regional and local outburst prediction indexes was compared. Gas content is more sensitive than gas pressure for composite coal seams. K1 can more accurately predict the outburst danger than Δh2 $\Delta {h}_{2}$ in composite coal seams.
Haijun Guo, Xi Xi, Kai Wang, Liang Wang, Yulin Li +4 more
wiley +1 more source

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infectious and parasitic diseases

carbonic anhydrases
surgery
molecular structure

dose-response relationship, drug
home hospice
humans