Results 151 to 160 of about 310,541 (331)

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Room‐Temperature Alane Dehydrogenation for Visible‐Light‐Driven Photocatalytic Hydrogen Supply System

Advanced Science, EarlyView.
In situ formed Al/MOF enables viable visible‐light‐driven photocatalytic dehydrogenation of alane (AlH3) confirming practical application. Results demonstrate that Al nanoparticles prolong lifetime of photogenerated charge carriers via localized surface plasmon resonance induced hot electron injection, while AlH3 chemisorption triggers interfacial ...
Ting‐Ting Li, Li‐Cheng Liang, Rui‐Qi Chen, Chun‐Qi Zhang, Sheng‐Nan Zhang, Wen‐Wen Cheng, Xi‐Hao Chen, Ning Wang, Juan‐Ding Xiao, Qing‐Qing Yang, Fei Liang, Chao‐Feng Zhang   +11 more
wiley   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

The Prognostic Significance of CTSV Expression in Patients with Hepatocellular Carcinoma

International Journal of General Medicine
Yuping He,1,2,* Minghao Xu,2,3,* Chenhao Zhou,2,3 Qiongzhu Dong,2,4 Zhiqiu Hu,2,4,5 Ning Ren2– 4 1School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, People’s Republic of China; 2Key ...
He Y, Xu M, Zhou C, Dong Q, Hu Z, Ren N
doaj  

HCCS 2024: 4th Workshop on Human-Centered Computational Sensing - Welcome and Committees [PDF]

Michele Girolami
openalex   +1 more source

Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA [PDF]

, 2018
Yin Li, Zhihui Cai, Baoan Zhu, Cunshuan Xu   +3 more
openalex   +1 more source

TKIs beyond immunotherapy predict improved survival in advanced HCC

, 2022
Samantha Armstrong, Tina Roy, Bhavana Singh, Monika Kulasekaran, Fatima Shaukat, Xue Geng, Hongkun Wang, Petra Prins, Reena Jha, Marion L. Hartley, Aiwu Ruth He   +10 more
openalex   +2 more sources

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source