Results 191 to 200 of about 160,497 (241)

Bidirectional Mendelian randomization analysis of the causal association between obesity and hepatocellular carcinoma in a European population. [PDF]

Medicine (Baltimore)
Ding X, Zhou X, Tang N, Wang X, Jin X, Ma X, Wu B, Wu C, Yang X, Yang J, Wu T, Liang Q, Yin L.   +12 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

<i>DNASE1L3</i> Mediates Hepatocellular Carcinoma Tumor Growth and Organoid Models via the Wnt/<b>β</b>-Catenin Signaling Pathway. [PDF]

Oncol Res
Zhang S, Zhao Y, Geng L, Song F, Feng L, Jiang J, Cai Q, Fan F.   +7 more
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Regulation of Autophagy and Metabolism in Hepatocellular Carcinoma: Involvement of Wnt-β-Catenin Pathway. [PDF]

J Cell Mol Med
Roy SK, Srivastava R, Landry N, Srivastava S, Shrivastava A, Srivastava RK.   +5 more
europepmc   +1 more source

Reframing Post‐Hepatectomy Liver Failure as a Determinant of Post‐Recurrence Survival in HCC

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Post‐hepatectomy liver failure (PHLF) is traditionally considered a transient perioperative complication with limited long‐term consequences, yet its long‐term oncologic implications in hepatocellular carcinoma (HCC) remain unclear. Methods Patients undergoing primary hepatectomy for HCC between 2007 and 2018 were analyzed.
Hiroshi Horie, Satoshi Ogiso, Tomoaki Yoh, Takahiro Nishio, Ken Fukumitsu, Yoichiro Uchida, Takamichi Ishii, Etsuro Hatano   +7 more
wiley   +1 more source

CCL11 promotes hepatocellular carcinoma recurrence after surgery by potentiating immunosuppressive CCR5 + CD206 + M2-like macrophages and promoting tumor invasiveness. [PDF]

Cell Death Dis
Wang J, Yeung OW, Qiu W, Pang L, Liu J, Yang X, Zeng S, Ding T, Wang Z, Hu Z, Cheung TT, Man K, Ng KT.   +12 more
europepmc   +1 more source

Relative telomer length as a potential biomarker in hepatocellular carcinoma: a comparative study of HCV patients treated with direct antiviral agent. [PDF]

BMC Cancer
Helal M, Gamal M, Basuni AA, El Gendy W, Khalil A.   +4 more
europepmc   +1 more source

CXCL1-overexpressing cancer-associated fibroblasts stimulate hepatocellular carcinoma progression via neutrophil recruitment, NET formation, and immune suppression. [PDF]

Cancer Immunol Immunother
Bi B, Tang L, Liang R, Wu H, Huang Q, Pan L.   +5 more
europepmc   +1 more source