Results 81 to 90 of about 289,858 (341)
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
International Journal of General Medicine, 2021 Danfeng Li,1,* Binlie Chen,1,2,* Yongming Zeng,1,* Huaiming Wang1 1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, People’s Republic of China; 2Medical college ...
Li D, Chen B, Zeng Y, Wang H
doaj
Prospective Phase II trial of drug-eluting bead chemoembolization for liver transplant candidates with hepatocellular carcinoma and marginal hepatic reserve. [PDF]
, 2019 Purpose: To determine whether chemoembolization using drug-eluting beads (DEB-TACE) is safe and effective for liver transplantation candidates with liver-limited hepatocellular carcinoma (HCC) without vascular invasion and baseline hepatic dysfunction ...
Fidelman, Nicholas +10 more
core +1 more source
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer [PDF]
, 2019 BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular Carcinoma (HCC).
Díaz Moreno, Irene +4 more
core +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
Advanced Healthcare Materials, EarlyView.The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao +7 more
wiley +1 more source
Cancer Management and Research, 2020 Hongliang Zang, Yuhui Li, Xue Zhang, Guomin Huang Department of General Surgery, China-Japan Union Hospital of Jilin University, Jilin, Changchun 130012, People’s Republic of ChinaCorrespondence: Guomin HuangDepartment of General Surgery, China ...
Zang H, Li Y, Zhang X, Huang G
doaj
Neoadjuvant Therapy for Hepatocellular Carcinoma
Journal of Hepatocellular Carcinoma, 2022 Zongyi Yin,1– 3 Dongying Chen,3,4 Shuang Liang,1 Xiaowu Li1– 3 1Department of Hepatobiliary Surgery, Shenzhen University General Hospital, Shenzhen University, Shenzhen, 518055, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Regional
Yin Z, Chen D, Liang S, Li X
doaj
New therapeutic targets in HCC: Reptin ATPase and HCC senescence
Journal of Hepatology, 2010 Cellular senescence is a process characterized by permanent cell cycle arrest. It is the consequence of the finite proliferative capacity of normal cells (replicative senescence) and the response to stress and damage from exogenous and endogenous sources.
openaire +3 more sources
Submission of Evidence on Online Violence Against Women to the UN Special Rapporteur on Violence Against Women, its Causes and Consequences, Dr Dubravka Šimonović [PDF]
, 2017 Figure S1. B3GALNT2 levels determined by W.B. and ROC curve. aâc Relative mRNA expression of B3GALNT2 in HCC tumor tissues and normal liver tissues obtained from GSE76427, GSE36376, and TCGA-LIHC datasets.
Jiangfan Zhou (5060249) +9 more
core +6 more sources