Results 151 to 160 of about 78,362 (247)

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella   +10 more
wiley   +1 more source

Cardiofaciocutaneous Syndrome Type 4 due to a MAP2K2 Variant: Expanding the Phenotypic Spectrum With Feeding Dysfunction and Neurodevelopmental Involvement

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT We report a female infant with cardiofaciocutaneous syndrome type 4 (CFC4), an ultra‐rare RASopathy caused by a heterozygous MAP2K2 (c.619G>A, p.Glu207Lys) variant. From birth, she presented with neonatal hypotonia, respiratory distress, and feeding dysfunction characterized by absent sucking reflex, orofacial hypotonia, and sensory ...
Aleksandra Świeca   +3 more
wiley   +1 more source

Ab Initio Calculation of Energy Gap and Optical Gap of Organic Semiconductors PTCDA and PDI

open access: yesChemPhysChem, Volume 27, Issue 3, February 2026.
We benchmark electronic structure methods for predicting energy and optical gaps of three organic semiconductors from molecules to crystals. GW is most reliable for crystalline energy levels, while single‐molecule time‐dependent density functional theory with a polarizable continuum model delivers remarkable accuracy for some quantities at a much lower
Chieh‐Min Hsieh   +4 more
wiley   +1 more source

CD56bright NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B‐cell‐depleting therapy

open access: yesClinical &Translational Immunology, Volume 15, Issue 2, 2026.
Antibody response to vaccination in people with multiple sclerosis receiving B‐cell depletion therapy is associated with B‐cell frequency but not time since B‐cell depletion. Immunoregulatory CD56bright NK cells may negatively impact antibody responses in this group.
Griffith B Perkins   +21 more
wiley   +1 more source

Coexistence of Hypertrophic Cardiomyopathy and Arterial Hypertension: Current Insights and Future Directions. [PDF]

open access: yesDiseases
Katsi V   +5 more
europepmc   +1 more source

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