Results 161 to 170 of about 29,714 (227)

Pharmacological Inhibition of Small Extracellular Vesicle Secretion by ALK5i SD‐208 via Lysosomal Rerouting of CD63+ Compartments

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Pharmacological tools to selectively modulate extracellular vesicle (EV) secretion are scarce. Here, we identify the ALK5 (TGF‐β receptor I) inhibitor SD‐208 as a potent suppressor of small EV (sEV) secretion that acts independently of its canonical anti‐fibrotic activity.
Rahul Sanwlani, Georgina H. Thompson, Kyle Bramich, Ching‐Seng Ang, Millie L. Trowbridge, Chris E. Duringer, Vlad Stolojan, Sean M. Davidson, Konstantinos Savvatis, John H. McVey, Suresh Mathivanan, Aled Clayton, Patrizia Camelliti   +12 more
wiley   +1 more source

Graphene‐Based Conductive Polymer Composites for Piezoresistive Sensors: Materials, Sensing Mechanisms, and Performance

Macromolecular Materials and Engineering, Volume 311, Issue 9, September 2026.
Graphene‐based conductive polymer composites are revolutionizing next‐generation piezoresistive sensors through synergistic conductive networks, ultrahigh sensitivity, and mechanical flexibility. This review critically analyzes recent advances in fabrication strategies, electromechanical sensing mechanisms, and quantitative performance metrics, while ...
Tran Van Khai, Nguyen Xuan Sang, KK Sadasivuni, Kumud M. Tripathi, Dusan Losic, Tran Thanh Tung   +5 more
wiley   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Uncertainty Quantification for Cardiac Diffusion Tensor Imaging Without Additional Datasets

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1458-1463, September 2026.
ABSTRACT Purpose Cardiac diffusion tensor imaging (cDTI) is subject to physiological noise, thermal noise, and signal corruption, which cause errors in diffusion measures. While a larger dataset can be decimated to investigate the general precision of measures from fitting smaller datasets, uncertainty quantification (UQ) methods for fitting entire ...
Sam Coveney, Irvin Teh, May Lwin, Mehak Asad, Isaac Watson, Maryam Afzali, Erica Dall'Armellina, Jürgen E. Schneider   +7 more
wiley   +1 more source

Captive Breeding Programme Enables a Successful Wētāpunga (Deinacrida heteracantha: Orthoptera: Anostostomatidae) Recovery Programme

New Zealand Journal of Zoology, Volume 53, Issue 3, September 2026.
Wētāpunga or Little Barrier Island giant wētā (Deinacrida heteracantha: Orthoptera: Anostostomatidae) underwent significant decline across Northland and Auckland, New Zealand, and by mid‐20th Century was restricted to Te Hauturu‐o‐Toi/Little Barrier Island.
Chris Green, Donald McFarlane, Ben Goodwin, Paul Barrett, Chye‐Mei Huang, Jessica Ayres, Richard Gibson   +6 more
wiley   +1 more source

Genotype‐Dependent Effects of Mechanical Stretch and GATA4‐Targeted Compound 3i‐1262 in Cardiomyopathy Patient–Derived hiPSC‐Cardiomyocytes

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Genetic hypertrophic and dilated cardiomyopathies (HCM and DCM, respectively) are characterised by structural and functional abnormalities that can lead to heart failure. However, current therapies mainly reduce symptoms. Patient‐derived human induced pluripotent stem cell (hiPSC)–derived cardiomyocytes provide a valuable platform to study ...
Saana Pohjavaara, Sini M. Kinnunen, Heikki Ruskoaho, Katriina Aalto‐Setälä, Mika J. Välimäki, Virpi Talman   +5 more
wiley   +1 more source

TUBA4A Pathogenic Variant Manifesting With Adulthood‐Onset Genetic Myasthenic Syndrome, Myopathy, and Infertility

European Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Objectives TUBA4A pathogenic variants are associated with ALS, frontotemporal dementia, spastic ataxia, spasticity, ataxia, Parkinson's disease, female infertility, macrothrombocytopenia, and myopathy. Four recently reported patients with TUBA4A neonatal/childhood onset myopathy had also a decrement on repetitive nerve stimulation (RNS), but ...
Margherita Milone, Stefan Nicolau, Zhiyv Niu, Teerin Liewluck, Eric J. Sorenson, Xin‐Ming Shen, C. Michael Harper, William J. Litchy   +7 more
wiley   +1 more source

Tuning the Mechanical Properties of Crosslinked Copolymers via Sequence and Solvent‐Selective Swelling for Vat Photopolymerization

Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.
Polymer sequence and solvent selectivity independently modulate pendant‐vinyl accessibility during photocuring, trapping different topologies in CLIP and controlling mechanical properties. ABSTRACT Block copolymers (BCPs) offer distinct advantages for vat photopolymerization by enabling mechanically programmable network structures through microphase ...
Chia‐Min Hsieh, Krista G. Schoonover, Naushad Ahmed, Jung‐Bin Ahn, Shuo Qian, Michael J. A. Hore, Weiling Xia, Kaiwen Hsiao, Yue Yuan, Mani Sengoden, Donald J. Darensbourg, Emily Pentzer, Peiran Wei   +12 more
wiley   +2 more sources

Primary Glaucoma in a Litter of Lop Rabbits

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To describe pectinate ligament dysplasia (PLD) and primary glaucoma in a litter of adult Lop rabbits. Animals Studied A litter of six adult Lop rabbits, three males and three females. Procedures The animals were surrendered to the shelter.
Melaney A. Mayes, Cory M. Howard, Ellen K. Gratch, Jamie C. Morrison, Kelsey A. Brakel, András M. Komáromy   +5 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, Volume 111, Issue 9, Page 3944-3967, 1 September 2026.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source