Results 151 to 160 of about 38,621 (286)
ABSTRACT This case describes a female infant with RAF1‐related Noonan syndrome who developed severe hypertrophic obstructive cardiomyopathy, pulmonary hypertension, and cardiorespiratory failure that responded to trametinib treatment but ultimately progressed to death following dose tapering and discontinuation of therapy. To the best of our knowledge,
C. Noah Nilsson +8 more
wiley +1 more source
ネットワークソフトウェアモデルやゲームプログラム制御では状態遷移図が使われている.状態遷移図にはセントラルコールモデル(CCMと略す)とハーフコールモデル(HCMと略す)の2つの代表的なモデルがある.2つのモデルはそれぞれに一長一短があり,両モデルの自動相互変換ができれば,お互いの長所を活かせて便利である.HCMからCCMへの変換手法はすでに提案されている.HCMではイベントの発生を全ての端末に通知し,イベント発生端末の周囲の状態がCCMで規定されているどの状態になっているかを探索する必要がある ...
TAKURA, Akira +9 more
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ABSTRACT A paradoxical rise in pulmonary artery pressure on follow‐up echocardiography after successful mavacamten therapy for obstructive hypertrophic cardiomyopathy (oHCM) prompted right heart catheterization, which demonstrated combined pre‐ and post‐capillary pulmonary hypertension and guided the decision to continue mavacamten while withholding ...
Mengdian Zhang
wiley +1 more source
The Future of HCM: Moving to the Cloud
The landscape of Human Capital Management (HCM) is undergoing a significant transformation as organizations increasingly migrate their HCM systems to the cloud.
Reddy Kommera, Harish Kumar
core +1 more source
Two Cases of Post‐Operative Coronary–Cameral Fistulas After Unusual Myectomy Procedures
Post‐surgical coronary–cameral fistulas (CCF) can occur after various myectomy procedures. Here we present one case of CCF after resection of the hypertrophied RV muscle bundle in double‐chambered RV (DCRV) and one case of CCF after subaortic web resection.
Neda Toofaninejad +3 more
wiley +1 more source
A 32‐Year‐Old Man With an Cardiomyopathy
ABSTRACT Scleredema is a sclerosing dermatosis of unknown etiology, characterized by non‐punctate, weakly infiltrated skin thickening and swelling, which can lead to the development of cardiomyopathy. Scleredema‐associated cardiomyopathy is at present poorly understood.
Yuting Zou, Shan Li, Tong Chen, Yi Li
wiley +1 more source
Electrophysiological Markers in Hypertrophic Cardiomyopathy: Enhancing Sudden Cardiac Death Risk Prediction with Index of Cardiac Electrophysiological Balance and Its Corrected Variant. [PDF]
Balaban İ +7 more
europepmc +1 more source
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam +2 more
wiley +1 more source
Integrative Transcriptomics and Machine Learning Identify Macrophage-Associated Biomarkers in Hypertrophic Cardiomyopathy. [PDF]
Zhao J +9 more
europepmc +1 more source
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality in children, but treatment options are limited. Aficamten, a next-in-class cardiac myosin inhibitor, directly targets the hypercontractility underlying HCM ...
Kaski, Juan Pablo +19 more
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