Results 141 to 150 of about 42,485 (257)

Computational Fluid Dynamics Based Diagnostics and Optimal Design of Hydraulic Capsule Pipelines [PDF]

Scarcity of fossil fuels and rapid escalation in the energy prices around the world is affecting efficiency of established modes of cargo transport within transportation industry.
Asim, Taimoor
core  

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson, Nathaniel Parker, Shiyi Wang, Sara Daley, Aaron Cote, Michael A. Winters   +5 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Barriers and Facilitators to Timely Detection and Optimal Management of Chronic Wet Cough in Aboriginal Children Across Australia From the Perspective of Health Care Providers: A Qualitative Study. [PDF]

Med J Aust
Lau GTY, Laird P, Aitken R, Barwick M, Bedford L, Bowden ER, Dalton C, Everingham J, Fuery A, Griffin R, Jain N, Kinghorn M, Knapp R, McCallum GB, Morris P, Norman R, Richmond PC, Saiganesh A, Sibosado S, Toombs M, Walker R, Wilson J, Chang AB, Schultz A.   +23 more
europepmc   +1 more source

Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP)

Biotechnology Progress, EarlyView.
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi, Nate Heller, Mohammadreza Ahmadimashhadi, Jon Petrone, Nicholas Marchand, Siavash Darvishmanesh, Ka Zhang, Stefano Menegatti, Andrew L. Zydney   +8 more
wiley   +1 more source

Translating knowledge gaps to practice: a knowledge, attitude and practice study based on 5A approach to improve smoking cessation training for healthcare providers in Karachi, Pakistan. [PDF]

BMJ Open
Mansoor J, Shakil M, Aqil H, Zehra W, Ijaz W, Mansoor F, Lal C, A Khan J, Fatmi Z.   +8 more
europepmc   +1 more source

DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography

Biotechnology Progress, EarlyView.
Abstract Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A specifically binds mAbs and
Lukas Döring, Sven Schubert, Nora Roos, Johannes Winderl, Annika Müller, Anna Ratermann, Matthias W. Kron, Jürgen Hubbuch   +7 more
wiley   +1 more source

Dual‐Function Electrocatalysis: Simultaneous Wastewater Remediation and Hydrogen Evolution—A Comprehensive Review

Carbon Energy, EarlyView.
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey, Rashid Al‐Hajri, Ala'a H. Al‐Muhtaseb, Hussein A. Younus, Mohammed Al‐Abri   +4 more
wiley   +1 more source

Resilience and Quality of Life: The Role of Positive Affect on Healthcare Professionals in High-Stress Environments. [PDF]

Worldviews Evid Based Nurs
Zusman N, Freeman MD, Andrews CS.
europepmc   +1 more source

Formic‐Acid In Situ Hydrogen Enables Programmable Ru–Pd–Pt/C Trimetallic Interfaces for Durable Acidic HER

Carbon Energy, EarlyView.
Bamboo diaphragm−derived carbon is used as a support to prepare Ru–Pd–Pt/C catalysts through a stepwise reduction strategy. The Ru–Pd interface promotes formic acid activation and induces Pt deposition. The metallic interface of Ru–Pd–Pt/C enables H* generation, transfer, and recombination, thereby improving Pt utilization, acidic HER activity, and PEM
Liangmeng Ni, Aiyue Huang, Xin Feng, Zhijia Liu   +3 more
wiley   +1 more source