Results 191 to 200 of about 36,523 (308)

Health Care Policy Implementation Trial of Primary Human Papillomavirus–Based Cervical Screening in Denmark

open access: yesInternational Journal of Cancer, EarlyView.
Uncertainty has persisted over whether human papillomavirus (HPV) testing outperforms high‐quality cytology in real‐world cervical cancer screening programs. To address this, Denmark launched a nationwide trial in 2021, implementing an HPV‐based screening strategy using specialized algorithms integrated with molecular and cytology triage to optimize ...
Jesper Bonde   +12 more
wiley   +1 more source

Changes in the gut microbiome during fasting‐induced molting and its effects on gut–liver function

open access: yesiMetaOmics, EarlyView.
During fasting, harmful microbiota and metabolites rise, triggering intestinal injury and activation of the TGF‐β signaling pathway, which enhances intestinal stem cell proliferation. Concurrently, hepatic function declines, indicated by increased hepatic and serum bile acids and upregulation of the non‐classical bile acid synthesis pathway.
Hao Zhang   +11 more
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

The Helping Alliance Questionnaire for Children and Their Caregivers—Validation in a German Sample of Pediatric Chronic Pain Patients

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objectives The “helping alliance” between patients, caregivers, and healthcare professionals (HCPs) plays an important role in the evaluation of therapeutic interventions. The aim of this study was to develop a German version of the Helping Alliance Questionnaire for pediatric patients (HAQ‐P) and caregivers (HAQ‐CG). Methods The questionnaire
Lisa‐Marie Rau   +2 more
wiley   +1 more source

A Study to Investigate Ghanaian Radiography Students' Proficiency, Experiences, Confidence, and Knowledge Concerning Communication With Hearing‐Impaired Patients

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This study investigated undergraduate Ghanaian radiography students' proficiency, experiences, confidence, and knowledge with regard to communicating with hearing‐impaired patients. It was found that although most students had some knowledge about effective communication strategies to be used with hearing‐impaired patients, their confidence levels were
Seth Kwadjo Angmorterh   +13 more
wiley   +1 more source

A post hoc analysis of linaclotide in pediatric patients with functional constipation and neurodevelopmental disorders

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person   +9 more
wiley   +1 more source

DaxibotulinumtoxinA for Injection in Adults with Cervical Dystonia: Clinical Insights from a Real‐World Early Experience Program

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background DaxibotulinumtoxinA for injection (DAXI), a novel botulinum toxin (BoNT) formulated with a custom‐engineered peptide, was recently approved for treating cervical dystonia (CD). DAXI demonstrated a long duration of symptom relief in Phase 3 trials. Objective To report findings from PrevU, an early experience, real‐world observational
Laxman Bahroo   +10 more
wiley   +1 more source

The WELLBEING Study: Exploring Healthcare Professionals (HCPs) Psychological Wellbeing at Work and Patients’ Experiences of Care

open access: yes
Kathryn Marie BamforthTitle: The WELLBEING Study: Exploring Healthcare Professionals (HCPs) Psychological Wellbeing at Work and Patients’ Experiences of CareBackground: HCPs’ psychological wellbeing affects patients’ experiences of care.
Bamforth, Kathryn
core  

Influence of Strain Rate on the Strain Hardening Behavior of a Lean Duplex Stainless Steel

open access: yesMetalMat, EarlyView.
The aim of this study was to examine how strain rate influences the compressive strain‐hardening behavior of a lean duplex stainless steel LDX 2101. Microstructural analysis using electron backscatter diffraction (EBSD) revealed a strain‐induced austenite‐to‐martensite transformation.
Akilakps Sawyerr   +4 more
wiley   +1 more source

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