Results 91 to 100 of about 28,210 (101)

Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

New England Journal of Medicine
BACKGROUND Bortezomib, lenalidomide, and dexamethasone (VRd) is a preferred first-line treatment option for patients with newly diagnosed multiple myeloma.
T. Facon, M. Dimopoulos, X. Leleu, M. Beksaç, L. Pour, R. Hájek, Zhuogang Liu, J. Minařík, P. Moreau, Joanna Romejko-Jarosinska, I. Špička, Vladimir I. Vorobyev, B. Besemer, Tadao Ishida, Wojciech Janowski, S. Kalayoglu-besisik, G. Parmar, P. Robak, E. Zamagni, Hartmut Goldschmidt, Thomas G. Martin, S. Manier, M. Mohty, Corina Oprea, Marie-France Brégeault, S. Macé, Christelle Berthou, David Bregman, Zandra K. Klippel, R. Orlowski   +29 more
semanticscholar   +1 more source

Ultra-sensitive pan-cancer molecular residual disease assessment using whole-genome sequencing-based personalized ctDNA panel: Initial results from the MONSTAR-SCREEN-3 project.

Journal of Clinical Oncology
3007 Background: While circulating tumor DNA (ctDNA) demonstrates promise as a molecular residual disease (MRD) biomarker, its clinical implementation has been primarily limited to tumors with favorable ctDNA shedding characteristics.
T. Hashimoto, S. Kobayashi, E. Oki, Y. Nakamura, Takahiro Kinoshita, Norio Nonomura, Kazuto Matsuura, Hidemich Watari, N. Gotohda, Takeo Fujita, Hiroji Iwata, K. Namikawa, Shingo Sakashita, Yoshikatsu Koga, Takao Fujisawa, Hideaki Bando, T. Yoshino, Jeff Jasper, K. Taber, Dale Muzzey   +19 more
semanticscholar   +1 more source

CARTITUDE-1 final results: Phase 1b/2 study of ciltacabtagene autoleucel in heavily pretreated patients with relapsed/refractory multiple myeloma.

Journal of Clinical Oncology, 2023
8009 Background: Heavily pretreated patients (pts) with relapsed/refractory multiple myeloma (RRMM) treated with standard of care therapy have median overall survival (OS) of ~12 months (mo). In the single-arm, phase 1b/2 CARTITUDE-1 study (NCT03548207),
Yi Lin, T. Martin, S. Usmani, J. Berdeja, A. Jakubowiak, M. Agha, A. Cohen, A. Deol, M. Htut, A. Lesokhin, Nikhil C. Munshi, E. O’Donnell, Carolyn C. Jackson, T. Yeh, A. Banerjee, E. Zudaire, D. Madduri, Christopher Delcorral, L. Bubuteishvili-Pacaud, S. Jagannath   +19 more
semanticscholar   +1 more source

The Factor Structure of Outcome Questionnaire–45.2 Scores Using Confirmatory Tetrad Analysis–Partial Least Squares

Journal of Psychoeducational Assessment, 2020
The researchers employed a confirmatory tetrad analysis (CTA) using partial least squares–structural equation modeling (PLS-SEM) with Outcome Questionnaire–45.2 (OQ-45) data, examining the measurement model of the OQ-45 scores with a sample of male adult
Saundra M. Tabet, Glenn W. Lambie, Shiva Jahani, Mostafa Rasoolimanesh   +3 more
semanticscholar   +1 more source

High‐Performance Bimodal Temperature/Pressure Tactile Sensor Based on Lamellar CNT/MXene/Cellulose Nanofibers Aerogel with Enhanced Multifunctionality

Advanced Functional Materials
The rapid development of thermoelectric‐piezoresistive dual‐mode sensors has opened new avenues for enhancing the functionality, miniaturization, and integration of flexible tactile sensors.
Lin Tian, Fu‐Lin Gao, Yu‐Xiao Li, Zhi‐Yue Yang, Xinghe Xu, Zhongjun Yu, Jie Shang, Run‐Wei Li, Xiaofeng Li   +8 more
semanticscholar   +1 more source

Pembrolizumab (pembro) for locally advanced (LA) or recurrent/metastatic (R/M) cutaneous squamous cell carcinoma (cSCC): Long-term results of the phase 2 KEYNOTE-629 study.

Journal of Clinical Oncology
9554 Background: Pembro monotherapy is approved in certain countries, including the US, for treatment of LA or R/M cSCC based on results from the open-label phase 2 KEYNOTE-629 trial (NCT03284424).
Eva Muñoz Couselo, B. Hughes, L. Mortier, Jean-Jacques Grob, Ralf Gutzmer, O. Roshdy, R. González Mendoza, Jacob Schachter, A. Arance, Florent Grange, Nicolas Meyer, A. Joshi, S. Billan, Sven Erik Ojavee, Jianda Yuan, B. Gumuscu, A. Bratland   +16 more
semanticscholar   +1 more source

The current status and influencing factors of oral frailty in elderly maintenance hemodialysis patients based on the Andersen Oral Health Outcome Model

BMC Oral Health
To analyse the elements that influence oral frailty in elderly maintenance hemodialysis patients and to comprehend the present state of this condition.
Meiqian Chen, Mingqian He, Qingxin Gu, Xinru Gao, Guanzhen Lu   +4 more
semanticscholar   +1 more source

Microplastics in the Coral Reef Systems from Xisha Islands of South China Sea.

Environmental Science and Technology, 2019
The impacts of microplastics on coral reefs are gaining attention due to findings that microplastics affect coral health. This work investigated the distribution and characteristics of microplastics in the seawater, fish, and corals in 3 atolls from the ...
Jinfeng Ding, F. Jiang, Jing-xi Li, Zongxing Wang, Chengjun Sun, Zhangyi Wang, L. Fu, Neal Xiangyu Ding, Changfei He   +8 more
semanticscholar   +1 more source

Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

Blood, 1999
T. Hamblin, Z. Davis, A. Gardiner, D. Oscier, F. Stevenson   +4 more
semanticscholar   +1 more source

Association of an educational program in mindful communication with burnout, empathy, and attitudes among primary care physicians.

Journal of the American Medical Association (JAMA), 2009
M. Krasner, R. Epstein, H. Beckman, A. Suchman, B. Chapman, C. Mooney, T. Quill   +6 more
semanticscholar   +1 more source