Results 41 to 50 of about 5,787 (90)

PENGETAHUAN REMAJA PUTRI TENTANG DAMPAK PERNIKAHAN DINI PADA KESEHATAN REPRODUKSI DI SMA BUDAYA BANDAR LAMPUNG

open access: yesJurnal Kebidanan Malahayati, 2019
Early marriage or young marriage is a marriage performed by a partner or one of their partners is still categorized as a teenager under 19 years. The practice of early marriage is most prevalent in Africa and Southeast Asia. In Southeast Asia, data shows
N. Isnaini, Ratna Sari
semanticscholar   +1 more source

The antitumor activity of umbelliferone in human renal cell carcinoma via regulation of the p110γ catalytic subunit of PI3Kγ

open access: yesActa Pharmaceutica, 2019
Umbelliferone exhibits extensive pharmacological activity, including anti-immunomodulatory, anti-inflammatory and antigenotoxicity activities. However, its antitumor properties still remain unclear in human renal cell carcinoma (RCC) cells.
Wang Xue   +5 more
doaj   +1 more source

Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells

open access: yesActa Pharmaceutica, 2023
Olive leaves as a main byproduct of olive oil and fruit industry are a valuable source of phytochemicals such as polyphenols, with multiple biomedical effects. Apart from leaves, olive branches and stems make up a significant amount of olive waste. It is
Benčić Đani   +7 more
doaj   +1 more source

Antimicrobial assesment of aroylhydrazone derivatives in vitro

open access: yesActa Pharmaceutica, 2019
Aroylhydrazones 1–13 were screened for antimicrobial and antibiofilm activities in vitro. N′-(2-hydroxy-phenylmethylidene)-3-pyridinecarbohydrazide (2), N′-(5-chloro-2-hydroxyphenyl-methylidene)-3-pyridinecarbohydrazide (10), N′-(3,5-chloro-2 ...
Polović Saša   +5 more
doaj   +1 more source

Curcumin-loaded nanostructured lipid carrier induced apoptosis in human HepG2 cells through activation of the DR5/caspase-mediated extrinsic apoptosis pathway

open access: yesActa Pharmaceutica, 2020
Curcumin is a lipophilic anti-cancer compound extracted from turmeric. Our previous study demonstrated that the curcumin-loaded nanostructured lipid carrier (Cur-NLC) exhibits superior anti-cancer activity in inhibiting proliferation as well as inducing ...
Wang Fengling   +6 more
doaj   +1 more source

Size exclusion chromatography as green support for forced degradation study of adalimumab

open access: yesActa Pharmaceutica, 2023
Size exclusion chromatography (SEC) has become a powerful tool for analysing size variants of biologic drugs in their native form. Modern SEC can be defined by the use of chromatographic columns packed with sub-3 µm particles, allowing an increase in ...
Kovačić Jelena   +3 more
doaj   +1 more source

Biopharmaceutical classification of desloratadine – not all drugs are classified the easy way

open access: yesActa Pharmaceutica, 2020
The biopharmaceutical classification of drugs was designed as a basis for bio-waivers – a mechanism with the double ethical benefit of delivering new drug formulations to the market with less human testing and lower cost.
Berginc Katja   +4 more
doaj   +1 more source

Rosuvastatin effects on the HDL proteome in hyperlipidemic patients

open access: yesActa Pharmaceutica, 2023
The advancements in proteomics have provided a better understanding of the functionality of apolipoproteins and lipoprotein-associated proteins, with the HDL lipoprotein fraction being the most studied.
Vavlukis Ana   +4 more
doaj   +1 more source

Synthesis and evaluation of bisulfate/mesylate-conjugated chlortetracycline with high solubility and bioavailability

open access: yesActa Pharmaceutica, 2020
The aim of this work is to improve the solubility and bioavailability of chlortetracycline and the function of the immune response. Chlortetracycline bisulfate and chlortetracycline mesylate were successfully synthesized and characterized with several ...
Liu Deng   +3 more
doaj   +1 more source

Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo

open access: yesActa Pharmaceutica, 2015
Free radicals are involved in the development of reperfusion injuries. Using a spin trap, the intensity of such lesions can be reduced. Nitrones (effective in vivo spin traps) were tried in this work as in vivo nitric oxide donors.
Croitoru Mircea Dumitru   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy