Results 231 to 240 of about 110,208 (302)

Pan-cancer analysis reveals HDAC1 as a key regulator of immune infiltration and T cell exhaustion. [PDF]

Discov Oncol
Wang X, Liu F, Tian W, Chao X, Li Y, Deng L, Sui S, Gao M.   +7 more
europepmc   +1 more source

Peripheral T‐Cell Lymphomas in Southern Taiwan: Epidemiology, Treatment Patterns, and Long‐Term Outcomes

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Peripheral T‐cell lymphomas (PTCLs) are heterogeneous neoplasms with poor prognosis and marked geographic variation. Data from Taiwan remain limited. We conducted a 15‐year retrospective cohort study of 249 patients diagnosed with PTCL at two major centers in southern Taiwan between 2010 and 2024 to characterize regional epidemiology, real ...
Bo‐Yu Huang, Li‐Chang Chang, Sheng‐Yen Hsiao, Ya‐Ping Chen, Sin‐Syue Li, Pei‐An Fu, Chen Chang, Kung‐Chao Chang, Tsai‐Yun Chen, Ya‐Ting Hsu   +9 more
wiley   +1 more source

Acetyl-Phosphate Dependent Protein Acetylation in Neisseria gonorrhoeae. [PDF]

Microbiologyopen
Parga EFD, Wolverson PA, Collins MO, Heaney O, Cole J, Green LR, Shaw JG.   +6 more
europepmc   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

MedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma, Qing Wang, Yusheng Zhang, Yang Li, Hongwei Wu, Hongjun Yang, Xianyu Li   +6 more
wiley   +1 more source

Effective Non-Invasive Delivery of Epigenetic Drugs Using Functionalized Accessory Unit Conjugates. [PDF]

Pharmaceutics
Tashima T.
europepmc   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source

Retraction: HDAC regulates the diabetic vascular endothelial dysfunction by targeting MnSOD. [PDF]

Biosci Rep
Liu Z, Hou Q, Hu K, Liu X, Quan J.
europepmc   +1 more source

Gastric Cancer: Pathobiology and Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu, Miao Zhang, Yan Meng, Chunxiao Zhu, Weihong Zhang, Hui Zhang, Zhifa Cao, Meihang Du, Zhangting Zhao, Junping Bai, Yi Han, Yang Tang, Wei Kang, Ka Fai To, Shi Jiao, Liwei An, Zhaocai Zhou   +16 more
wiley   +1 more source

Epigenetic Alterations in Microbiome-Host Interactions in Inflammatory and Autoimmune Diseases. [PDF]

Int J Mol Sci
Basher AA, Rejili M, Ahmed AA, Essa MOA, Ibrahim NA, Basher NS, Husien HM, Saleh AA, Abdulrahman MY, Jan RU, Adam SY, Cai D.   +11 more
europepmc   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang, Qitai Chen, YuJie Yu, Yi Zang, Rujia Zheng, Zhe Zhang, Shuaijun Lu, Li Zhou   +7 more
wiley   +1 more source