Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling [PDF]
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Yang T +11 more
europepmc +2 more sources
Mechanistic Study of Ru-NHC-Catalyzed Hydrodefluorination of Fluoropyridines: The Influence of the NHC on the Regioselectivity of C–F Activation and Chemoselectivity of C–F versus C–H Bond Cleavage [PDF]
We describe a combined experimental and computational study into the scope, regioselectivity, and mechanism of the catalytic hydrodefluorination (HDF) of fluoropyridines, C5F5–xHxN (x = 0–2), at two Ru(NHC)(PPh3)2(CO)H2 catalysts (NHC = IPr, 1, and IMes,
Whittlesey, Michael K. +19 more
core +1 more source
Computational study of the hydrodefluorination of fluoroarenes at [Ru(NHC)(PR3)2(CO)(H)2]: predicted scope and regioselectivities [PDF]
Density functional theory calculations have been employed to investigate the scope and selectivity of the hydrodefluorination (HDF) of fluoroarenes, C6F6-nHn (n = 0-5), at catalysts of the type [Ru(NHC)(PR3)(2)(CO)(H)(2)].
Panetier, Julien A. +7 more
core +1 more source
Background and ObjectiveThe effect of chronic pulmonary regurgitation (PR) on right ventricular (RV) dysfunction in repaired Tetralogy of Fallot (RTOF) patients is well recognized by cardiac magnetic resonance (CMR).
Yue-Hin Loke +11 more
doaj +1 more source
Prospective Audit of Colonoscopy Practice in a Lebanese University Hospital
Background Colonoscopy has a great impact on diagnosis and management of the diseases of the colon. In general it's a safe and accurate procedure. No evaluation has been done of any endoscopic practices in a country where the practice of medicine is ...
Rita Slim +6 more
doaj +1 more source
Background Online hemodiafiltration (OL-HDF), whether in pre-dilution OL-HDF (pre-HDF) or post-dilution OL-HDF (post-HDF), is conducted to efficiently remove low molecular weight proteins from the blood of patients requiring dialysis.
Kenji Sakurai +3 more
doaj +1 more source
Targeted-Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy. [PDF]
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Xing H +9 more
europepmc +2 more sources
HDF5 1.10.6 unmodified source code
HDF5 1.10.6 unmodified source code. The HDF Group doesn't provide a direct download link, but the license does give the freedom to distribute.
HDF Group, HDF Group (8424786)
core +1 more source
Metadata Life Cycles, Use Cases and Hierarchies
The historic view of metadata as “data about data” is expanding to include data about other items that must be created, used, and understood throughout the data and project life cycles.
Ted Habermann
doaj +1 more source
Broadband surface acoustic wave attenuation in metals using chirp compression and dispersive interdigital transducers [PDF]
This study presents a non-destructive method for estimating surface acoustic wave attenuation, which is highly sensitive to microstructural features, especially at high frequencies.
Dame Fall +4 more
doaj +1 more source

