Results 1 to 10 of about 717 (134)

Nine‐Year Follow‐Up After M‐TEER for Secondary Mitral Regurgitation in a Patient With Cardiogenic Shock

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter edge‐to‐edge repair (TEER) has become an established therapeutic option for patients with severe secondary mitral regurgitation (SMR). While randomized trials and registry data have reported outcomes up to 5 years, longer follow‐up data remain scarce.
Tobias Reithmayer, Thomas J. Stocker, Ludwig T. Weckbach, Julia Novotny, Philipp M. Doldi, Hannah Kempton, Steffen Massberg, Michael Näbauer, Jörg Hausleiter, Lukas Stolz   +9 more
wiley   +1 more source

Machine learning‐based predictive models versus traditional risk scores in hemodialysis patients with comorbid urolithiasis

Precision Medical Sciences, EarlyView.
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain, Muhammad Riaz, Mirza Muhammad Hadeed Khawar, Jawad Hameed, Malik Sohail Riaz   +4 more
wiley   +1 more source

Comparison of Biocompatibility and Efficacy of Regional Citrate Anticoagulation and Unfractionated Heparin During Expanded Hemodialysis With a Medium Cut‐Off Membrane: A Randomized Trial

Artificial Organs, Volume 50, Issue 6, Page 809-812, June 2026.
In a randomized cross‐over trial, regional citrate anticoagulation provided superior biocompatibility over full‐dose unfractionated heparin during expanded hemodialysis with significantly lower activation of complement, granulocytes, and platelets without affecting dialysis efficiency. ABSTRACT Background Regional citrate anticoagulation (RCA) improves
Marija Malgaj Vrečko, Jernej Pajek, Jakob Gubenšek, Samo Hudoklin, Joško Osredkar, Mojca Božič Mijovski, Aleš Jerin, Jadranka Buturović‐Ponikvar   +7 more
wiley   +1 more source

Midazolam Dosing During CRRT: A Combined Ex Vivo and Physiologically‐Based Pharmacokinetic Approach

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Children supported with continuous renal replacement therapy have high mortality rates ranging from 30% to 70%. The cause of this high mortality is multifactorial and includes ineffective drug dosing and altered drug pharmacokinetics. Changes in drug exposure can result from (1) underlying disease; and (2) direct drug interaction and/or ...
Autumn M. McKnite, Abdullah Hamadeh, J. Porter Hunt, Danielle J. Green, Carina Imburgia, Aviva Whelan, Rachel Hudson, Andrew Chevalier, Cheryl L. Mathis, Michelle J. Yang, Jamie P. Dwyer, Andrea Edginton, Kevin M. Watt   +12 more
wiley   +1 more source

Determinants of Intradialytic Phosphate Removal in Hemodiafiltration From Real‐World Clinical Practice

Artificial Organs, Volume 50, Issue 5, Page 755-763, May 2026.
We show that convective therapy in the form of hemodiafiltration does not demonstrate a measurable effect on phosphate removal in a real‐world setting. On the other hand, session duration is the most important factor in determining phosphate removal in hemodialysis patients.
David A. Jaques, Roohi Chhabra, Haalah Shaaker, Priyanka Khatri, Andrew Davenport   +4 more
wiley   +1 more source

Impact of Expanded Hemodialysis on Inflammation and Iron Metabolism in Chronic Hemodialysis Patients

Seminars in Dialysis, Volume 39, Issue 3, Page 105-115, May/June 2026.
ABSTRACT Microinflammation and functional iron deficiency are major contributors to anemia and treatment burden in maintenance hemodialysis (HD). Medium cutoff (MCO) membranes enhance the removal of middle‐ and large‐sized solutes implicated in these pathways, yet real‐world data using routinely measured inflammatory and iron‐related markers are scarce.
Berrak Itır Aylı, Gülay Ulusal Okyay, Mehmet Deniz Aylı   +2 more
wiley   +1 more source

Controversy on the CONVINCE study findings: the PRO take

Brazilian Journal of Nephrology
The CONVINCE study, recently published in the New England Journal of Medicine, reveals a groundbreaking 23% reduction in the relative risk of all-cause mortality among end-stage kidney patients undergoing high convective volume hemodiafiltration.
Bernard Canaud, Peter Blankestijn
doaj   +2 more sources

Interdialytic blood pressure is independent of weight gain and correlated with serum angiotensin II levels in adults

Physiological Reports, Volume 14, Issue 9, May 2026.
Abstract Chronic volume overload is a major risk factor of hypertension and mortality in chronic dialysis patients. However, the mechanisms responsible for hypertension are unclear. We studied 32 patients (age 23–68 years, 19 females) in chronic hemodiafiltration classified by their interdialytic ambulatory blood pressure (idABP, mmHg) in three groups:
Adolfo Diaz, Brenda Delgado, Eduardo R. Argaiz, Olynka Vega, Ricardo Correa‐Rotter, Bernardo Rodriguez‐Iturbe   +5 more
wiley   +1 more source

Differences in Dialysis Efficacy Have Limited Effects on Protein-Bound Uremic Toxins Plasma Levels over Time

Toxins, 2019
The protein-bound uremic toxins para-cresyl sulfate (pCS) and indoxyl sulfate (IS) are associated with cardiovascular disease in chronic renal failure, but the effect of different dialysis procedures on their plasma levels over time is poorly studied ...
Detlef H. Krieter, Simon Kerwagen, Marieke Rüth, Horst-Dieter Lemke, Christoph Wanner   +4 more
doaj   +1 more source

A Case Report of Acute Renal Failure due to Amlodipine Overdose and Alcohol Consumption

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Amlodipine intoxication is clinically common yet life‐threatening, usually resulting in severe cardiovascular collapse and end‐organ hypoperfusion. Here, we report a case of a 46‐year‐old male with amlodipine (420 mg) and ethanol intoxication who unexpectedly presented without severe hypotension or shock.
Yi Xi
wiley   +1 more source