Results 51 to 60 of about 21,030,393 (234)

Correlations between HDL-C and HDL-P (panel A), and HDL-C and HDL size (panel B) in a virtual population of 2000 subjects.

, 2014
Correlations between HDL-C and HDL-P (panel A), and HDL-C and HDL size (panel B) in a virtual population of 2000 subjects.
James Lu (534847), M. Nazeem Nanjee (534848), Katrin Hübner (88740), Eliot A. Brinton (434267), Norman A. Mazer (534849)   +4 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Comorbidities of Obesity in a Rural African Population Residing in Limpopo Province, South Africa: A Comparison between General and Central Obesity

Obesities
Obesity is a growing epidemic that threatens to deplete healthcare resources by increasing the prevalence of diabetes, heart disease, high blood pressure, cancer, and chronic kidney disease.
Cairo B. Ntimana, Reneilwe G. Mashaba, Kagiso P. Seakamela, Eric Maimela, Matshane L. Masemola-Maphutha, Solomon S. R. Choma   +5 more
doaj   +1 more source

EFEITO DA IDADE E DO SEXO DE PARAIBANOS SOBRE A BIOQUÍMICA DO SANGUE: II – NÍVEIS DE COLESTEROL TOTAL, LDL-C, HDL-C E TRIGLICÉRIDES

Revista de Ciências da Saúde Nova Esperança, 2005
Esta pesquisa foi realizada com o objetivo de avaliar os níveis sanguíneos de colesterol total, LDL-C, HDL-C e triglicérides. A população estudada foi selecionada a partir de uma amostragem aleatória simples, constituiu-se de 220 pacientes, sendo 102 do ...
Carolina Uchôa Guerra Barbosa, Homero Perazzo Barbosa, Margareth de Fátima Formiga Melo Diniz   +2 more
doaj   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

The relationship between non-HDL-C/HDL-C ratio and bone mineral density: an NHANES study

Frontiers in Nutrition
BackgroundThe non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a newly developed lipid parameter. However, the current research has only explored the relationship with lumbar spine bone mineral density ...
Shuo Qi, Biao Peng, Zhanwang Xu, Daodi Qiu, Guoqing Tan   +4 more
doaj   +1 more source

Differential response to low-fat diet between low and normal HDL-cholesterol subjects

Journal of Lipid Research, 2000
: Heart attacks frequently occur in normolipidemic subjects with low concentration of high density lipoproteins (≤35 mg/dL). A low-fat diet is generally recommended to patients with coronary heart disease.
Bela Asztalos, Michael Lefevre, Laurence Wong, Theda A. Foster, Richard Tulley, Marlene Windhauser, Wenwu Zhang, Paul S. Roheim   +7 more
doaj   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source