Results 71 to 80 of about 21,030,393 (234)

Proinflammatorikus HDL vizsgálata

, 2010
Hazánkban a kardiovaszkuláris megbetegedések sajnálatos módon előkelő helyen állnak a halálozási statisztikákban, amelyen belül is az érelmeszesedésnek kiemelt szerepe van. Az érelmeszesedés hátterében a koleszterinháztartás egyensúlyának eltolódása áll,
Lőrincz, Hajnalka
core  

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu, Shuting Huang, Leilei Zhu, Junyi Huang, Kewei Li, Guangming Li, Jiannong Wu, Mingyuan Zhou, Fangmei Zhou, Zhishan Ding, Yingzhi Shen   +10 more
wiley   +1 more source

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source

The non-linear link between non-high-density lipoprotein to high-density lipoprotein ratio and the risk of stroke in middle-aged and older adults in Chinese: a prospective cohort study from the China health and retirement longitudinal study

Frontiers in Endocrinology
ObjectiveThis study aims to assess the association between the non-HDL-c/HDL-c ratio and stroke risk among middle-aged and older adults participating in the China Health and Retirement Longitudinal Study (CHARLS).MethodsThis study conducted a prospective
Lanbo Wang, Yong Han, Yong Han, Changchun Cao, Haofei Hu, Haofei Hu, Han Li   +6 more
doaj   +1 more source

Receiver operating characteristic (ROC) curves of TG/HDL-C, TG, and HDL-C for insulin resistance.

, 2016
The area under the ROC curve ± standard error (95% CI):TG/HDL-C: 0.70 ± 0.03(0.65–0.75); TG: 0.69 ± 0.03(0.64–0.74); HDL-C: 0.37 ± 0.03(0.31–0.42). Abbreviations: TG:triglyceride; HDL-C:high-density lipoprotein cholesterol; TG/HDL-C:triglyceride to high ...
Zeng.ai Chen (2626813), Yaomin Hu (2626807), Tingting Han (1437814), Yangxue Li (1678933), Xingxing Ren (2626810), Shuang Zheng (768179), Wei Liu (20030)   +6 more
core   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

The relationship between high density lipoprotein subclass profile and plasma lipids concentrations

Lipids in Health and Disease, 2010
HDL particles posses multiple antiatherogenic activities and the identification and differentiation of individual HDL subclasses may be useful in documentation and understanding of metabolic changes of different HDL subclasses.
Tian Li, Fu Mingde
doaj   +1 more source

Evaluation of triglyceride: HDL-C ratio and Non-HDL-C as harbingers of increased cardiovascular risk in metabolic syndrome [PDF]

, 2016
Background: Metabolic syndrome is an aggregate of conditions that together increases the risk of developing cardiovascular disease and type 2 diabetes mellitus.
R., Dharuni, R., Harish, H. L., Vishwanath, B. V., Maruthi Prasad   +3 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

HDL-C concentration is related to markers of absorption and of cholesterol synthesis: Study in subjects with low vs. high HDL-C

, 2011
Background: The antiatherogenic functions of high density lipoprotein (HDL-C) include its role in reverse cholesterol transport, but to what extent the concentration of HDL-C interferes with the whole-body cholesterol metabolism is unknown. Therefore, we
NAKANDAKARE, E. R., NUNES, V. S., LEANCA, C. C., PANZOLDO, N. B., QUINTAO, E. C. R., FARIA, E. C. de, CAZITA, P. M., PARRA, E.   +7 more
core   +1 more source