Results 81 to 90 of about 21,030,393 (234)

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

The Relationship Between Non-HDL-C /HDL-C Ratio (NHHR) and Vitamin D in Type 2 Diabetes Mellitus

Diabetes, Metabolic Syndrome and Obesity, 2023
Ruoxi Zhen,1,2 Jiangli Ban,2,3 Zhuoya Jia,1,2 Yanhui Liu,2,3 Zelin Li,1,2 Shuchun Chen1,2,4 1Graduate School, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Endocrinology, Hebei General Hospital, Shijiazhuang ...
Zhen R, Ban J, Jia Z, Liu Y, Li Z, Chen S   +5 more
doaj  

A Technology Aware Magnetic QCA NCL-HDL Architecture [PDF]

, 2009
Magnetic Quantum Dot Cellular Automata (MQCA) have been recently proposed as an attractive implementation of QCA as a possible CMOS technology substitute.
Graziano, Mariagrazia, Chiolerio, Alessandro, Zamboni, Maurizio   +2 more
core  

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Relationships between lipid profiles and metabolic syndrome, insulin resistance and serum high molecular adiponectin in Japanese community-dwelling adults

Lipids in Health and Disease, 2011
Background There are few studies to demonstrate the associations between newly addressed lipid profiles and metabolic syndrome (MetS)-associated variables.
Takayama Shuzo, Kusunoki Tomo, Miki Tetsuro, Kohara Katsuhiko, Tabara Yasuharu, Kawamoto Ryuichi, Abe Masanori, Katoh Tateaki, Ohtsuka Nobuyuki   +8 more
doaj   +1 more source

Quantitative Assessment of Baseline Serum HDL-C to Predict Gout Flares During Urate-Lowering Therapy Initiation: A Prospective Cohort Study [PDF]

Chang Jiang,1,2 Maichao Li,1,2 Ying Chen,3 Yuwei He,1,2 Xinde Li,1,2 Lingling Cui,1,2 Han Qi,1,2 Zan Cheng,1,2 Xiaoqing Zhang,3 Changgui Li,1– 3 Jie Lu1– 3 1Shandong Provincial Clinical Research Center for Immune Diseases and Gout, Qingdao, People’s ...
Li X, He Y, Li C, Cui L, Qi H, Zhang X, Lu J, Jiang C, Chen Y, Li M, Cheng Z   +10 more
core  

Pengaruh Pemberian Ekstrak Air Tebu Hitam (saccharum officinarum l.) Terhadap Kadar High Densitylipoprotein(hdl) Serum Mencit (mus musculus) Yang Diinduksi Diet Tinggi Kolesterol [PDF]

, 2018
Hiperkolesterolemia adalah keadaan terjadinya peningkatan kadar kolesterol dalam darah. Peningkatan kadar kolesterol total dan penurunan kadar HDL merupakan faktor risiko terjadinya penyakit kardiovaskular dan metabolik.
Ana Fama, Mardhatilla
core  

Low LDL-C and High HDL-C Levels Are Associated with Elevated Serum Transaminases amongst Adults in the United States: A Cross-sectional Study [PDF]

, 2014
Background: Dyslipidemia, typically recognized as high serum triglyceride, high low-density lipoprotein cholesterol (LDL-C) or low high-density lipoprotein cholesterol (HDL-C) levels, are associated with nonalcoholic fatty liver disease (NAFLD). However,
Jiang, Zhenghui, Yusuke Tsugawa, Kenneth Mukamal (509754), Elliot Tapper (509755), Simon C Robson, Elliot Tapper, Zhenghui Gordon Jiang (509753), Simon C. Robson (301209), Kenneth Mukamal, Mukamal, Kenneth, Tsugawa, Yusuke, Robson, Simon, Jiang, Zhenghui Gordon, Tapper, Elliot, Robson, Simon C, Yusuke Tsugawa (509756), Zhenghui Gordon Jiang   +16 more
core   +2 more sources

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source