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HDL Function and Atherosclerosis: Reactive Dicarbonyls as Promising Targets of Therapy

Circulation Research, 2023
Epidemiologic studies detected an inverse relationship between HDL (high-density lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease (ASCVD), identifying HDL-C as a major risk factor for ASCVD and suggesting ...
M. Linton, P. Yancey, H. Tao, S. Davies
semanticscholar   +1 more source

HDL Structure

2022
HDL has various protein components, including enzymes, complement components, apolipoproteins, protease inhibitors, etc. In addition to proteins, lipids are also a significant component of HDL. These components and their structure determine the function of HDL. HDL is heavily involved in the acute response phase, complement regulation phase, hemostasis
Siying, Deng, Yangkai, Xu, Lemin, Zheng
openaire   +2 more sources

HDL functionality

Current Opinion in Lipidology, 2012
HDL cholesterol concentration is inversely correlated with cardiovascular disease and has a wide range of functions involved in many systems. The purpose of this review is to summarize HDL functionality, its relevance to atherosclerosis and factors affecting HDL functions.The contribution of HDL to reverse cholesterol transport may not be as great as ...
Handrean, Soran   +3 more
openaire   +2 more sources

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