Results 301 to 310 of about 428,492 (343)
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HDL Subfractions, HDL Receptors and HDL Turnover
1987Plasma lipoproteins can be classified according to density, size or electrophoretic mobility. The latter is based on the apolipoprotein composition. Alaupovic1 proposed a distinction between so-called simple lipoproteins, containing only one apolipoprotein, and complex lipoproteins, containing more than one apolipoprotein. Recent publications show that
van Tol, A. +3 more
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Monocyte‐to‐HDL‐cholesterol ratio as a prognostic marker in cardiovascular diseases
Journal of Cellular Physiology, 2018Inflammation and lipid accumulation are two basic hallmarks of atherosclerosis as a chronic disease. Inflammation not only is a local response but can also be considered as a systemic process followed by an elevation of inflammatory mediators.
S. Ganjali +6 more
semanticscholar +1 more source
2022
Since therapeutic strategies designed to raise HDL failed to exert the expected effective cardiovascular disease (CVD) outcomes in clinical trials, how to improve HDL function rather than its plasma level has become a new focus of scientists' attention. Numerous HDL mimetic peptides have been designed and investigated in various animal models in recent
Jie, Chen, Jiewen, Liu, Baoqi, Yu
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Since therapeutic strategies designed to raise HDL failed to exert the expected effective cardiovascular disease (CVD) outcomes in clinical trials, how to improve HDL function rather than its plasma level has become a new focus of scientists' attention. Numerous HDL mimetic peptides have been designed and investigated in various animal models in recent
Jie, Chen, Jiewen, Liu, Baoqi, Yu
openaire +2 more sources
2022
Sepsis has been recognized as a global health burden in the year 2017 for its high morbidity and mortality. HDL, a cholesterol transporter, also plays vital role in inflammation besides its typical role in reverse cholesterol transportation. In septic patients, HDL levels dropped significantly.
Huanhuan, Cao, Wei, Huang
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Sepsis has been recognized as a global health burden in the year 2017 for its high morbidity and mortality. HDL, a cholesterol transporter, also plays vital role in inflammation besides its typical role in reverse cholesterol transportation. In septic patients, HDL levels dropped significantly.
Huanhuan, Cao, Wei, Huang
openaire +2 more sources
2022
Diabetes is a worldwide public health issue, with the number of cases expected to reach 642 million by 2040. Patients with diabetes are at a two- to four-fold increased risk of developing cardiovascular disease. This chapter focuses on the anti-diabetic and cardioprotective functions of plasma high-density lipoproteins (HDLs).
Blake J, Cochran +2 more
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Diabetes is a worldwide public health issue, with the number of cases expected to reach 642 million by 2040. Patients with diabetes are at a two- to four-fold increased risk of developing cardiovascular disease. This chapter focuses on the anti-diabetic and cardioprotective functions of plasma high-density lipoproteins (HDLs).
Blake J, Cochran +2 more
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2022
A wealth of evidence indicates that high-density lipoprotein assumes the unique antiatherosclerosis and other cardioprotective properties. Based on that, HDL-C has been considered as a promising therapy target to reduce the cardiovascular diseases.
Ke, Li, Xianwei, Xie, Yansong, Guo
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A wealth of evidence indicates that high-density lipoprotein assumes the unique antiatherosclerosis and other cardioprotective properties. Based on that, HDL-C has been considered as a promising therapy target to reduce the cardiovascular diseases.
Ke, Li, Xianwei, Xie, Yansong, Guo
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HDL and atherosclerosis: Insights from inherited HDL disorders
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015Plasma high density lipoproteins (HDL) comprise a highly heterogeneous family of lipoprotein particles, differing in density, size, surface charge, and lipid and protein composition. Epidemiological studies have shown that plasma HDL level inversely correlates with atherosclerotic cardiovascular disease.
L. Calabresi +4 more
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2022
In this chapter, we summarize the relationship between circulating high-density lipoprotein (HDL) and atherosclerotic cardiovascular disease (ASCVD). HDL acts in many types of cells, such as endothelial cell, macrophage, T lymphocyte, etc. Recently, novel HDL-related therapies have been developed to treat ASCVD.
Hongtu, Cui, Qian, Du
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In this chapter, we summarize the relationship between circulating high-density lipoprotein (HDL) and atherosclerotic cardiovascular disease (ASCVD). HDL acts in many types of cells, such as endothelial cell, macrophage, T lymphocyte, etc. Recently, novel HDL-related therapies have been developed to treat ASCVD.
Hongtu, Cui, Qian, Du
openaire +2 more sources
2022
In this chapter, we will focus on HDLs' activity of inhibiting LDL oxidation and neutralizing some other oxidants. ApoA-I was known as the main antioxidant component in HDLs. The regulation of antioxidant capacity of HDL is mainly exhibited in regulation of apoA-I and alterations at the level of the HDL lipidome and the modifications of the proteome ...
Qi, Zhang, Zongzhe, Jiang, Yong, Xu
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In this chapter, we will focus on HDLs' activity of inhibiting LDL oxidation and neutralizing some other oxidants. ApoA-I was known as the main antioxidant component in HDLs. The regulation of antioxidant capacity of HDL is mainly exhibited in regulation of apoA-I and alterations at the level of the HDL lipidome and the modifications of the proteome ...
Qi, Zhang, Zongzhe, Jiang, Yong, Xu
openaire +2 more sources
2022
In addition to the well-known functions, plasma HDL also plays an important role in postsurgery periods. In this chapter, we summarized the changes of HDL after surgery like bariatric surgery and cardiac surgery. Not only the amount of HDL changed, the HDL components or functions have also been altered after various surgeries.
Yue-Ming, Peng, Jing-Song, Ou
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In addition to the well-known functions, plasma HDL also plays an important role in postsurgery periods. In this chapter, we summarized the changes of HDL after surgery like bariatric surgery and cardiac surgery. Not only the amount of HDL changed, the HDL components or functions have also been altered after various surgeries.
Yue-Ming, Peng, Jing-Song, Ou
openaire +2 more sources