Results 311 to 320 of about 428,492 (343)
Some of the next articles are maybe not open access.
2022
In previous chapters, we know that high-density lipoproteins (HDLs) could act at multiple cell lines and then trigger intracellular molecular pathway to prevent several metabolic diseases. Besides the classic genes regulating cholesterol efflux and reverse cholesterol transport (RCT), microRNAs (miRNAs) could also affect HDLs biogenesis, metabolism ...
Hongtu, Cui, Kaixuan, Lv, Nana, Yang
openaire +2 more sources
In previous chapters, we know that high-density lipoproteins (HDLs) could act at multiple cell lines and then trigger intracellular molecular pathway to prevent several metabolic diseases. Besides the classic genes regulating cholesterol efflux and reverse cholesterol transport (RCT), microRNAs (miRNAs) could also affect HDLs biogenesis, metabolism ...
Hongtu, Cui, Kaixuan, Lv, Nana, Yang
openaire +2 more sources
Colesterol HDL bajo o hipofunción HDL
Medicina Clínica, 2012El colesterol unido a las lipoproteinas de alta densidad (cHDL) es un excelente factor de riesgo cardiovascular en la practica totalidad de las poblaciones estudiadas hasta la actualidad. En realidad, el cHDL es el mejor predictor de riesgo lipidico junto a la concentracion de colesterol no-HDL, y la alteracion lipidica mas frecuente en sujetos que ...
Fernando Civeira, Elena Burillo
openaire +1 more source
High-density Lipoprotein (HDL) Dysfunction and the Future of HDL.
Current Vascular Pharmacology, 2017Although High Density Lipoprotein Cholesterol (HDL-C) levels are inversely proportional to cardiovascular risk in many studies, recent pharmacological interventional studies with HDL-C raising strategies did not show a benefit in terms of vascular events.
S. Ertek
semanticscholar +1 more source
Current Opinion in Lipidology, 2015
To summarize the current evidence concerning the role of HDL-C and HDL-associated parameters in the risk for cardiovascular disease (CVD).Numerous population studies have shown that plasma levels of HDL-C are inversely associated with CVD risk; in patient care HDL-C levels are therefore widely implemented in risk estimation models.
G Kees, Hovingh +2 more
openaire +2 more sources
To summarize the current evidence concerning the role of HDL-C and HDL-associated parameters in the risk for cardiovascular disease (CVD).Numerous population studies have shown that plasma levels of HDL-C are inversely associated with CVD risk; in patient care HDL-C levels are therefore widely implemented in risk estimation models.
G Kees, Hovingh +2 more
openaire +2 more sources
Current Pharmaceutical Design, 2014
High density lipoprotein cholesterol (HDL-C) and its related apolipoproteins form part of the reverse cholesterol transport system that removes excessive cholesterol from the periphery to the liver. Many transport proteins and enzymes that are involved in this process are susceptible to genetic defects that influence plasma HDL-C concentrations and HDL
Devaki R, Nair, Arun, Nair, Anjly, Jain
openaire +2 more sources
High density lipoprotein cholesterol (HDL-C) and its related apolipoproteins form part of the reverse cholesterol transport system that removes excessive cholesterol from the periphery to the liver. Many transport proteins and enzymes that are involved in this process are susceptible to genetic defects that influence plasma HDL-C concentrations and HDL
Devaki R, Nair, Arun, Nair, Anjly, Jain
openaire +2 more sources
LDL and HDL Subfractions, Dysfunctional HDL: Treatment Options
Current Pharmaceutical Design, 2014Low-density lipoproteins (LDL) are considered as important risk factors for cardiovascular diseases (CVD), while highdensity lipoproteins (HDL) are well recognized for their putative role in reverse cholesterol transport and other atheroprotective functions.
Garcia-Rios, Antonio +5 more
openaire +3 more sources
2011
Menno Vergeer onderzocht de genetische basis van het menselijk HDL-cholesterolmetabolisme door middel van familieonderzoek en genetische associatiestudies in grote cohorten. Mutaties in verschillende cholesterolvervoerders zijn van invloed op de productie van insuline in de alvleesklier en van steroïdhormonen in de bijnier. Daarnaast blijken genetische
openaire +1 more source
Menno Vergeer onderzocht de genetische basis van het menselijk HDL-cholesterolmetabolisme door middel van familieonderzoek en genetische associatiestudies in grote cohorten. Mutaties in verschillende cholesterolvervoerders zijn van invloed op de productie van insuline in de alvleesklier en van steroïdhormonen in de bijnier. Daarnaast blijken genetische
openaire +1 more source
1986
There is considerable inferential evidence that the high density lipoproteins (HDL) of mammalian plasma should have greater structural and functional heterogeneity than has been so far established. It is likely that at least transitory progenitors of HDL originating from hepatic and intestinal cells will differ from one another, perhaps forming ...
openaire +2 more sources
There is considerable inferential evidence that the high density lipoproteins (HDL) of mammalian plasma should have greater structural and functional heterogeneity than has been so far established. It is likely that at least transitory progenitors of HDL originating from hepatic and intestinal cells will differ from one another, perhaps forming ...
openaire +2 more sources