Utility of the serum alanine aminotransferase to high density lipoprotein cholesterol ratio in evaluating nonalcoholic fatty liver disease and liver fibrosis. [PDF]
Xuan Y+5 more
europepmc +1 more source
Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav+3 more
wiley +1 more source
A cross sectional study of the diabetes mediated GGT to HDL ratio and cognitive function in older adults. [PDF]
Wang Y+7 more
europepmc +1 more source
ABSTRACT Background To evaluate the associations of systemic diseases with AMD incidence and explore whether polygenic risk score (PRS) for AMD influences these associations. To assess the impacts of polymorbidities and serum biomarkers on AMD risk. Methods This prospective study of 471156 AMD‐free UK Biobank participants assessed systemic diseases ...
Jun Yu+9 more
wiley +1 more source
Optimisation of lipid-lowering therapy post-Acute Coronary Syndromes: a multidisciplinary, cross-interface novel pharmacy care model within a local cardiac rehabilitation centre. [PDF]
Gul IZ+6 more
europepmc +1 more source
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
Inflammation mediated glycolipid dysregulation in coronary microvascular disease pathogenesis. [PDF]
Wen W+10 more
europepmc +1 more source
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina+15 more
wiley +1 more source
HDL-C and visceral adipose tissue as combined predictors of visceral fat changes following laparoscopic sleeve gastrectomy. [PDF]
Sun Y+6 more
europepmc +1 more source
In this randomized crossover study, 29 participants with increased cardiometabolic risk consumed four isoenergetic, isonitrogenous meals containing 25 or 50 g of canola or coconut oil. Blood samples (e.g., for analysis of lipid, glucose, and insulin metabolism) were collected in the fasting state and 0.5, 1.0, 1.5, 2.0, 3.0, 4.0, 5.0, and 6.0 h ...
Hannah F. Kienēs+8 more
wiley +1 more source