Results 151 to 160 of about 933,327 (380)
Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials
Chronic Diseases and Translational Medicine, EarlyView. ABSTRACT
Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra +6 morewiley +1 more sourceLow levels of HDL-cholesterol and endothelial dysfunction: a systematic review and meta-analysis [PDF]
, 2018 Leonardo Roever, Elmiro Santos Resende, Angélica Lemos, Debs Diniz, Nilson Penha‐Silva, João Lucas O’Connell, Fernanda Rodrigues de Souza, Poliana Rodrigues, Alves Duarte, Paulo Fernando, Silva Gomes, Américo José, Caixeta Neto, Lívia Ambrósio Da Silva, Rosangela De Oliveira, Hugo Ribeiro Zanetti, Anaisa Silva Roerver-Borges, Fernando Veloso, Thiago Montes Fidale, Antonio Casella–Filho, Paulo Magno, Martins Dourado, Carlos Antônio, Palandri Chagas, Sadeq Ali‐Hasan‐Al‐Saegh, Paulo Eduardo Ocke Reis, Rogério De, Melocosta Pinto, Gustavo B.F. Oliveira, Álvaro Avezum, Mansueto Gomes Neto, André Rodrigues Durães, Rose Ferreira Lisboa Da Silva, Antônio José Grande, Renato D. Lópes, Shahab Alizadeh, Adrían V. Hernández, Maria Inês da Rosa, Gary Tse, Tong Liu, Giuseppe Biondi‐Zoccai, Giuseppe Biondi-Zoccai, S Ahmed, H Rehman, J Akeroyd, Gbf Oliveira, A Avezum, L Roever, L Roever, G Biondi-Zoccai, A Chagas, L Roever, E Resende, A Diniz, N Penha-Silva, F Veloso, L Roever, E Resende, Ald Diniz, L Roever, E Resende, F Veloso, A Diniz, N Penha-Silva, M Van Rooy, E Pretorius, N Sarrafzadegan, M Gharipour, M Sadeghi, P Nezafati, M Talaie, L Snchez-Iigo, D Navarro-Gonzlez, A Fernndez-Montero, J Pastrana-Delgado, J Martnez, C Chei, K Yamagishi, T Tanigawa, A Kitamura, H Imano, M Kiyama, X Fang, H Liu, X Zhang, H Zhang, X Qin, Ji, D Moher, A Liberati, J Tetzlaff, D Altman, L Shamseer, D Moher, M Clarke, D Ghersi, A Liberati, M Petticrew, P Shekelle, L Stewart +99 moreopenalex +1 more sourceEvaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice
ChemMedChem, EarlyView.A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...Amanda K. J. P. F. da Silva, Eucilene K. de L. B. Marques, Lidiane M. A. de Lima, Widarlane A. S. Alves, Dayane A. Gomes, Pedro L. Guzzo, Mônica F. Belian, Wagner E. Silva, Eduardo C. Lira +8 morewiley +1 more sourcePrognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation
Clinical Pharmacology &Therapeutics, EarlyView.From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...Hyun Woong Park, Jae‐Hwan Lee, Jin‐Ok Jeong, Diana A. Gorog, Udaya S. Tantry, Byeong‐Keuk Kim, Hyung Joon Joo, Kiyuk Chang, Jin‐Yong Hwang, Young Bin Song, Sung Gyun Ahn, Jung‐Won Suh, Woong Gil Choi, Jung Rae Cho, Jeehoon Kang, Sang Yeub Lee, Hyo‐Soo Kim, Moo Hyun Kim, Do‐Sun Lim, Eun‐Seok Shin, Paul A. Gurbel, Young‐Hoon Jeong, on behalf of the PTRG‐DES Consortium Investigators +22 morewiley +1 more sourceWeight loss surgery in adolescents corrects high-density lipoprotein subspecies and their function. [PDF]
, 2017 Background/objectiveYouth with obesity have an altered high-density lipoprotein (HDL) subspecies profile characterized by depletion of large apoE-rich HDL particles and an enrichment of small HDL particles.Davidson, WS, Elder, D, Heink, A, Hui, DY, Inge, TH, Kelesidis, T, Melchior, JT, Sexmith, H, Shah, AS +8 morecore +1 more sourceUntargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
Clinical Pharmacology &Therapeutics, EarlyView.Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik +12 morewiley +1 more sourceMulticenter evaluation of a homogeneous assay for HDL-cholesterol without sample pretreatment [PDF]
, 1997 Matthias Nauck, Winfried März, Jochen Jarausch, Christa M. Cobbaert, Anja Sägers, Dirk Bernard, Joris Delanghe, Gunter Honauer, Paul F. Lehmann, Evelyn Oestrich, Arnold von Eckardstein, Stephan G. Walch, Heinrich Wieland, Gerd Assmann +13 moreopenalex +1 more source