The Current Status of Research on High-Density Lipoproteins (HDL): A Paradigm Shift from HDL Quantity to HDL Quality and HDL Functionality [PDF]
International Journal of Molecular Sciences, 2022 The quantity of high-density lipoproteins (HDL) is represented as the serum HDL-C concentration (mg/dL), while the HDL quality manifests as the diverse features of protein and lipid content, extent of oxidation, and extent of glycation.
Kyung‐Hyun Cho
exaly +3 more sources
Native High-Density Lipoproteins (HDL) with Higher Paraoxonase Exerts a Potent Antiviral Effect against SARS-CoV-2 (COVID-19), While Glycated HDL Lost the Antiviral Activity. [PDF]
Antioxidants (Basel), 2021 Human high-density lipoproteins (HDL) show a broad spectrum of antiviral activity in terms of anti-infection. Although many reports have pointed out a correlation between a lower serum HDL-C and a higher risk of COVID-19 infection and progression, the in
Cho KH, Kim JR, Lee IC, Kwon HJ.
europepmc +2 more sources
Loss of sphingosine 1-phosphate (S1P) in septic shock is predominantly caused by decreased levels of high-density lipoproteins (HDL). [PDF]
J Intensive Care, 2019 BackgroundSphingosine 1-phosphate (S1P) is a signaling lipid essential in regulating processes involved in sepsis pathophysiology, including endothelial permeability and vascular tone. Serum S1P is progressively reduced in sepsis patients with increasing
Winkler MS +6 more
europepmc +2 more sources
The pleiotropic vasoprotective functions of high density lipoproteins (HDL). [PDF]
J Biomed Res, 2017 The pleiotropic functions of circulating high density lipoprotein (HDL) on peripheral vascular health are well established. HDL plays a pivotal role in reverse cholesterol transport and is also known to suppress inflammation, endothelial activation and ...
Boyce G, Button E, Soo S, Wellington C.
europepmc +2 more sources
Microencapsulated Pomegranate Modifies the Composition and Function of High-Density Lipoproteins (HDL) in New Zealand Rabbits [PDF]
Molecules, 2020 Previous studies demonstrated that pomegranate, which is a source of several bioactive molecules, induces modifications of high-density lipoproteins (HDL) lipid composition and functionality.
Alan Dorantes-Morales +9 more
doaj +2 more sources
Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression. [PDF]
PLoS One, 2017 We use a computational model to explore the effect of foam cell accumulation on plaque regression following an increase in high density lipoprotein (HDL) influx into the plaque.
Chalmers AD, Bursill CA, Myerscough MR.
europepmc +2 more sources
Associations between lipoproteins and risk of ischemic stroke: a systematic review and meta-analysis of Mendelian randomization studies [PDF]
Frontiers in NeurologyObjectiveTo systematically evaluate the causal effects of lipoproteins on ischemic stroke (IS) through a systematic review and meta-analysis of Mendelian randomization (MR) studies.MethodsA comprehensive literature search was conducted in PubMed, Embase,
Yanwei Guo +9 more
doaj +2 more sources
High-density lipoproteins (HDL): Novel function and therapeutic applications.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2021 The failure of high-density lipoprotein (HDL)-raising agents to reduce cardiovascular disease (CVD) together with recent findings of increased cardiovascular mortality in subjects with extremely high HDL-cholesterol levels provide new opportunities to ...
M. Darabi, A. Kontush
semanticscholar +1 more source
High-density lipoproteins may play a crucial role in COVID-19
Virology Journal, 2022 Background Lipids play a central role in the virus life cycle and are a crucial target to develop antiviral therapeutics. Importantly, among the other lipoproteins, the ‘good cholesterol’ high-density lipoprotein (HDL) has been widely studied for its ...
Minu Nain +3 more
doaj +1 more source
JDS Communications, 2022 Quantification of serum lipoproteins provides information relative to the overall metabolic health, degree of lipid mobilization, and hepatic function of dairy cattle.
E. Behling-Kelly, C. Wong
doaj +1 more source