Results 41 to 50 of about 57,933 (305)

High-density lipoproteins (HDL): Novel function and therapeutic applications

open access: yes, 2021
International audienceThe failure of high-density lipoprotein (HDL)-raising agents to reduce cardiovascular disease (CVD) together with recent findings of increased cardiovascular mortality in subjects with extremely high HDL-cholesterol levels provide ...
Darabi, Maryam, Kontush, Anatol
core   +1 more source

High-density lipoprotein (HDL) metabolism and bone mass [PDF]

open access: yesJournal of Endocrinology, 2017
It is well appreciated that high-density lipoprotein (HDL) and bone physiology and pathology are tightly linked. Studies, primarily in mouse models, have shown that dysfunctional and/or disturbed HDL can affect bone mass through many different ways.
Nicholaos I, Papachristou   +3 more
openaire   +2 more sources

Zymosan phagocytosis by mouse peritoneal macrophages is increased by apoHDL- and not by intact HDL-covered particles

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The uptake of lipids and lipoprotein particles by macrophages undergoes phagocytic activation and the formation of foam cells are key events in atherosclerosis.
M.D.T. Carvalho   +5 more
doaj   +1 more source

Nascent high density lipoproteins from liver perfusates of orotic acid-fed rats.

open access: yesJournal of Lipid Research, 1990
Uniformly fatty livers from orotic acid-fed rats secreted almost no very low density lipoproteins (VLDL) but normal amounts of nascent high density lipoproteins (HDL) accumulated in perfusates.
R L Hamilton   +4 more
doaj   +1 more source

Subfractions of high-density lipoprotein (HDL) and dysfunctional HDL in chronic kidney disease patients [PDF]

open access: yesArchives of Medical Science, 2016
A number of studies have shown that chronic kidney disease (CKD) is associated with increased risk for cardiovascular disease (CVD). Chronic kidney disease is characterized by significant disturbances in lipoprotein metabolism, including differences in quantitative and qualitative content of high-density lipoprotein (HDL) particles. Recent studies have
Rysz-Górzyńska, Magdalena   +1 more
openaire   +2 more sources

Secretion from cell culture of HDL and VLDL bearing apoB-33 with a large internal deletion

open access: yesJournal of Lipid Research, 1997
Rat hepatoma McA-RH7777 cells synthesize and secrete two populations of apoB-containing lipoproteins: a larger, VLDL-sized population floating in the Sf 40-150 range and a smaller, LDL and HDL-sized population. Three permanently transfected cell lines of
M J Wu   +7 more
doaj   +1 more source

Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia

open access: yesMolecular Neurodegeneration, 2023
This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to cognitive impairment and dementia (VCID).
Tetiana Poliakova, Cheryl L. Wellington
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Suppression of Endothelial Cell Apoptosis by High Density Lipoproteins (HDL) and HDL-associated Lysosphingolipids [PDF]

open access: yesJournal of Biological Chemistry, 2001
Apoptotic cell death following injury of vascular endothelium is assumed to play an important role in the pathogenesis of atherosclerosis. In this report, we demonstrate that high density lipoproteins (HDL), a major anti-atherogenic lipoprotein fraction, protect endothelial cells against growth factor deprivation-induced apoptosis.
J R, Nofer   +7 more
openaire   +2 more sources

Prognostic Value of Circulating Lipoprotein in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Lipoproteins have been reported to be associated with prognosis in various cancers; however, the prognostic value of lipoproteins in patients with nasopharyngeal carcinoma (NPC) remains largely unknown.
Ji-Jin Yao   +8 more
doaj   +1 more source

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