Results 51 to 60 of about 494,667 (340)

Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]

, 2018
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty, Hui, Hussain, Lin, Mahley, Pepe, Roselaar   +6 more
core   +2 more sources

Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins

Journal of Lipid Research, 2000
Phospholipid transfer protein gene knock-out (Pltp KO) mice have defective transfer of very low density lipoprotein (VLDL) phospholipids into high density lipoprotein (HDL) and markedly decreased HDL levels (Jiang et al. 1999. J. Clin. Invest.
Shucun Qin, Koichi Kawano, Can Bruce, Min Lin, Charles Bisgaier, Alan R. Tall, Xian-cheng Jiang   +6 more
doaj   +1 more source

Zymosan phagocytosis by mouse peritoneal macrophages is increased by apoHDL- and not by intact HDL-covered particles

Brazilian Journal of Medical and Biological Research, 2000
The uptake of lipids and lipoprotein particles by macrophages undergoes phagocytic activation and the formation of foam cells are key events in atherosclerosis.
M.D.T. Carvalho, V.E. Tobias, C.M.V. Vendrame, A.F.M. Shimabukuro, M. Gidlund, E.C.R. Quintão   +5 more
doaj   +1 more source

Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. [PDF]

, 2019
BACKGROUND: The relevance of blood lipid concentrations to long-term incidence of cardiovascular disease and the relevance of lipid-lowering therapy for cardiovascular disease outcomes is unclear.
Alver, M. (Maris), Amouyel, P. (Philippe), Bakker, S.J.L. (Stephan), Benjamin, E.J. (Emelia J.), Blankenberg, S. (Stefan), Bobak, M. (Martin), Brambilla, P. (Paolo), Brenner, H. (Hermann), Brunner, F.J. (Fabian J), Costanzo, S. (Simona), Dallongeville, J., de Lemos, J.A. (James A), Dobson, A. (Annette), Donfrancesco, C. (Chiara), Drygas, W. (Wojciech), Dullaart, R.P.F. (Robin P.F.), Dörr, M. (Marcus), Eliasson, M. (Mats), Engström, G., Ferrières, J. (Jean), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giles, G. (Graham), Grassi, G. (Guido), Hodge, A. (Allison), Hveem, K. (Kristian), Iacoviello, L. (Licia), Ikram, M.K. (M. Kamran), Ingelsson, M. (Martin), Jorgensen, T. (Torben), Jousilahti, P. (Pekka), Jääskeläinen, T. (Tuija), JöCkel, K.-H. (Karl-Heinz), Kavousi, M. (Maryam), Kee, F. (F.), Klotsche, J. (Jens), Koenig, W. (Wolfgang), Kontto, J. (Jukka), Kuulasmaa, K. (Kari), Lackner, K.J. (Karl), Landmesser, U. (Ulf), Leistner, D.M. (David M), Linneberg, A. (Allan), Lorenz, T. (Thiess), Lyngbakken, M.N. (Magnus N.), Magliano, D.J., Makarova, N. (Nataliya), Malyutina, S., Mathiesen, E.B. (Ellisiv), Meisinger, C. (Christa), Melander, O. (Olle), Metspalu, A. (Andres), Moitry, M. (Marie), Männistö, S. (Satu), Nauck, M. (Matthias), Niiranen, T. (Teemu), Nikitin, Y., Ojeda, F. (Francisco), Omland, T. (Torbjørn), Pajak, A. (Andrzej), Panagiotakos, D.B. (Demosthenes), Peters, A. (Annette), Pitsavos, C. (Christos), Riserus, U. (Ulf), Salomaa, V. (Veikko), Sans, S. (Susana), Schmidt, B. (Börge), Schöttker, B. (Ben), Shaw, J.E., Shea, S. (Steven), Signorini, S. (Stefano), Simons, L.A. (Leon), Söderberg, S. (Stefan), Tamosiunas, A. (Abdonas), Thorand, B. (Barbara), Tunstall-Pedoe, H. (Hugh), Twerenbold, R. (Raphael), Vasan, R.S. (Ramachandran Srini), Veronesi, G. (Giovanni), Völzke, H. (Henry), Waldeyer, C. (Christoph), Wannamethee, S.G. (Goya), Whincup, P.H. (Peter), Wild, P.S. (Philipp), Wilsgaard, T. (Tom), Woodward, M. (Mark), Zeller, T. (Tanja)   +86 more
core   +10 more sources

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

Nascent high density lipoproteins from liver perfusates of orotic acid-fed rats.

Journal of Lipid Research, 1990
Uniformly fatty livers from orotic acid-fed rats secreted almost no very low density lipoproteins (VLDL) but normal amounts of nascent high density lipoproteins (HDL) accumulated in perfusates.
R L Hamilton, L S Guo, T E Felker, Y S Chao, R J Havel   +4 more
doaj   +1 more source

The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]

, 1997
Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
Gent, T. van, Jong-Caesar, R. de, Katan, M.B., Roos, B. de, Scheek, L. M., Tol, A. van, Urgert, R.   +6 more
core   +3 more sources

Promotion of lymphocyte growth by high density lipoproteins (HDL). Physiological significance of the HDL binding site.

Journal of Biological Chemistry, 1989
The characteristics and physiological relevance of the high density lipoprotein (HDL) binding site on unstimulated and mitogen activated human peripheral blood lymphocytes have been investigated.
G. Jürgens, Qingbo Xu, L. Huber, G. Böck, H. Howanietz, G. Wick, K. Traill   +6 more
semanticscholar   +1 more source

Molecular simulation of discoidal HDL lipoprotein particles

, 2023
High-density lipoprotein (HDL) has been determined to play an essential role as an atheroprotective in atherosclerosis – the thickening and hardening of arteries. HDL particles are important delivery vehicles in the reverse cholesterol transport (RCT) pathway wherein excess cholesterol is removed from peripheral tissues and transported to the liver for
Siddiq, Hind, Anwar, Jamshed
openaire   +3 more sources

Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia

Molecular Neurodegeneration, 2023
This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to cognitive impairment and dementia (VCID).
Tetiana Poliakova, Cheryl L. Wellington
doaj   +1 more source