Results 21 to 30 of about 2,768,031 (303)

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo

Journal of Lipid Research, 2009
Uptake of cholesterol from peripheral cells by nascent small HDL circulating in plasma is necessary to prevent atherosclerosis. This process, termed reverse cholesterol transport, produces larger cholesterol-rich HDL that transfers its cholesterol to the
Frank M. Sacks, Lawrence L. Rudel, Adam Conner, Hassibullah Akeefe, Gerhard Kostner, Talal Baki, George Rothblat, Margarita de la Llera-Moya, Bela Asztalos, Timothy Perlman, Chunyu Zheng, Petar Alaupovic, Jo-Ann B. Maltais, H. Bryan Brewer   +13 more
doaj   +1 more source

Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells.

Journal of Lipid Research, 1983
The objective of this study was to determine whether high density lipoproteins (HDL) that have been treated with hepatic lipase have an enhanced ability to deliver cholesterol to cells.
M Bamberger, J M Glick, G H Rothblat
doaj   +1 more source

Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaireds⃞

Journal of Lipid Research, 2007
Recently, we showed that holo HDL particle uptake and resecretion occur in physiologically relevant cell lines and that HDL uptake is mediated by scavenger receptor class B type I (SR-BI).
Tamara A. Pagler, Angelika Neuhofer, Hildegard Laggner, Wolfgang Strobl, Herbert Stangl   +4 more
doaj   +1 more source

Paradoxical mortality differential of HDL cholesterol

Asian Journal of Medical Sciences, 2023
High-density lipoprotein (HDL) cholesterol has been known for ages to be cardio-protective due to its defensive action against genesis of atherosclerosis.
Jyotishman Mukhopadhyay , Debayan Mallik , Sughandha Garg   +2 more
doaj   +1 more source

Apolipoprotein M promotes cholesterol uptake and efflux from mouse macrophages

FEBS Open Bio, 2021
Apolipoprotein M (ApoM) exhibits various anti‐atherosclerotic functions as a component of high‐density lipoprotein (HDL) particles. Scavenger receptor class B type I (SR‐BI) is a classic HDL receptor that mediates selective cholesterol uptake and ...
Shuang Yao, Fan Zheng, Yang Yu, Yuxia Zhan, Ning Xu, Guanghua Luo, Lu Zheng   +6 more
doaj   +1 more source

Genetic Variation in FADS Genes and Plasma Cholesterol Levels in 2-Year-Old Infants [PDF]

, 2013
Single nucleotide polymorphisms (SNPs) in genes involved in fatty acid metabolism (FADS1 FADS2 gene cluster) are associated with plasma lipid levels. We aimed to investigate whether these associations are already present early in life and compare the ...
Moltó-Puigmartí Carolina, Penders, J., Ronald P Mensink, Carolina Moltó-Puigmartí (5261441), Jogchum Plat (302633), Thijs Carel, Monique Mommers, Thijs, Carel, Mommers, Monique, Eugène Jansen, Dirkje S Postma, Mensink Ronald P., John Penders (396322), Mommers Monique, Plat, J., Mensink, Ronald P., Koppelman, Gerard H., Standl Marie, Dirkje S. Postma (101740), Joachim Heinrich (60421), Postma, D.S., Jansen, Eugène, Standl, Marie, Moltó-Puigmartí, Carolina, Penders John, Koppelman Gerard H., Heinrich Joachim, Mensink, R.P., Thijs, C., Gerard H. Koppelman (153163), Postma, Dirkje S., Moltó-Puigmarti, C., Plat Jogchum, Carolina Moltó-Puigmartí, Carel Thijs (112720), Postma Dirkje S., Jansen, E., Joachim Heinrich, Marie Standl, Carel Thijs, Heinrich, Joachim, Jogchum Plat, Mommers, M., Standl, M., Monique Mommers (112709), Heinrich, J., Ronald P. Mensink (302629), Koppelman, Gerard H.; id_orcid, John Penders, Eugène Jansen (123572), Marie Standl (163136), Thijs, C.; id_orcid, Plat, Jogchum, Penders, John, Gerard H Koppelman, Koppelman, G.H., Jansen Eugène   +56 more
core   +3 more sources

Cholesterol transport between cells and high density lipoprotein subfractions from obese and lean subjects

Journal of Lipid Research, 1998
We studied the pathway of cholesterol efflux from fibroblasts by testing plasma samples from obese and lean subjects. Plasma samples were incubated with [3H]cholesterol-labeled human skin fibroblasts for 1 h to ensure uniform labeling of all of the high ...
Takayuki Sasahara, Paul Nestel, Noel Fidge, Dmitri Sviridov   +3 more
doaj   +1 more source

Independent association of atherogenic dyslipidaemia with all‐cause mortality in individuals with type 2 diabetes and modifying effect of gender: a prospective cohort study

Cardiovascular Diabetology, 2021
Background Atherogenic dyslipidaemia has been implicated in the residual risk for cardiovascular morbidity and mortality, which remains despite attainment of LDL cholesterol goals especially in individuals with type 2 diabetes.
Emanuela Orsi, Giuseppe Penno, Anna Solini, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Franco Cavalot, Susanna Morano, Marco G. Baroni, Antonio Nicolucci, Giuseppe Pugliese, for the Renal Insufficiency And Cardiovascular Events (RIACE) Study Group   +12 more
doaj   +1 more source

Lipid panel with Non-HDL cholesterol and total cholesterol/HDL cholesterol ratio

Abant Medical Journal, 2015
OBJECTIVE: In our study, the importance of the computational tests such as non-HDL cholesterol and Total cholesterol to HDL ratio for evaluating blood lipid levels were investigated.METHODS: The measured and calculated lipid parameters of 683 patients whose test inputs were done from Family Medicine Clinic were evaluated.
YÜKSEL, Hatice, KAPLAN, İbrahim, CELEPKOLU, Tahsin, TOPRAK, Gülten, AYDENİZ, Nurefşan, ETİK, Emel, ÇOLPAN, Leyla   +6 more
openaire   +3 more sources

Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection [PDF]

, 2011
High density lipoprotein cholesterol (HDL) and its component sphingosine-1-phosphate (S1P) protect against myocardial infarction. Recently, the SAFE (survivor activating factor enhancement) pathway, involving tumour necrosis factor (TNF) and the ...
Hacking, Damian
core   +1 more source