Results 201 to 210 of about 108,215 (261)

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Eight weeks of running, but not stationary cycling, training attenuates the vestibulosympathetic reflex in healthy adults. [PDF]

J Appl Physiol (1985)
Ray CA, Domeier C, Sauder CL.
europepmc   +1 more source

A tandem reinforcement learning framework for localized prostate cancer treatment planning and machine parameter optimization

Medical Physics, Volume 53, Issue 2, February 2026.
Abstract Background Volumetric modulated arc therapy (VMAT) machine parameter optimization (MPO) is a complex, high‐dimensional problem typically solved with inverse planning solutions that are both temporally and computationally expensive. While machine learning techniques have been explored to automate this process, they often supplement rather than ...
Nathan Shaffer, Avinash Reddy Mudireddy, Joel St‐Aubin   +2 more
wiley   +1 more source

HDR, etc.

Pierre Kaser, 2015
openaire   +2 more sources

Is Moderately Hypofractionated Radiotherapy a Safe and Effective Strategy for Cervical Cancer?-A Review of Current Evidence. [PDF]

Curr Oncol
Xiao H, Guo F, Wang Z, Pei K, Wei S, Qu A, Wang J, Jiang P.   +7 more
europepmc   +1 more source

Generation of 3D reference dosimetric datasets towards adoption of model‐based dose calculations for permanent implant prostate brachytherapy

Medical Physics, Volume 53, Issue 2, February 2026.
Abstract Purpose This work aims to create and validate a comprehensive set of test cases and 3D reference dosimetric datasets for model‐based dose calculation algorithms (MBDCAs) in permanent implant prostate brachytherapy. These test cases address the limits of the standard TG‐43 formalism towards improving dose evaluations in prostate cancer ...
Fatemeh Akbari, Vasiliki Peppa, Samuel Ouellet, Narjes Moghadam, Sandra Oliver, Vicent Gimenez‐Alventosa, Luc Beaulieu, Javier Vijande, Rowan M. Thomson   +8 more
wiley   +1 more source

Activity-dependent transit dose assessment in ¹⁹²Ir high-dose-rate brachytherapy surface applicator using GafChromic^TM EBT4 film. [PDF]

Precis Radiat Oncol
Liu D, Draeger E, Tien CJ, Guan F.
europepmc   +1 more source

Combining flat‐panel imaging with internal BB markers for precise HDR brachytherapy source localization: A simulation study

Medical Physics, Volume 53, Issue 2, February 2026.
Abstract Background High Dose Rate (HDR) brachytherapy delivers concentrated radiation to the tumor by placing a high‐dose‐rate radioactive source directly inside the target. However, the sharp dose falloff also increases susceptibility to errors and uncertainties.
Yibin Ling, Catherine H. Frank, Naoki Dominguez Kondo, Jose Ramos Mendez, Ke Sheng, Qihui Lyu   +5 more
wiley   +1 more source

Strategies to improve the efficiency of homing gene drives with multiplexed gRNAs. [PDF]

BMC Biol
Chen W, Wu P, Champer J.
europepmc   +1 more source