Results 121 to 130 of about 10,931 (234)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

High dynamic range shortwave infrared imaging of mice with an InGaAs camera. [PDF]

J Biomed Opt
Patel A, Zhong X, Moffett M, Sun Y, Dennis AM.   +4 more
europepmc   +1 more source

Patient‐Derived Organoid‐Based CRISPR Screens in Cancer Research: Applications, Advances, and Challenges

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Patient‐derived organoids (PDOs) have emerged as physiologically relevant cancer models that preserve key genetic, histological, and functional features of the tumors from which they are derived. In parallel, CRISPR‐based perturbation technologies have transformed functional genomics by enabling scalable interrogation of gene function.
Julianne du Plessis, Aadilah Omar
wiley   +1 more source

Adaptive tunneling photodiodes enable visual recognition in high-contrast scenes. [PDF]

Sci Adv
Liu L, Hu F, Han J, Gou J, Zou P, Yu H, He M, Guo L, Lian Y, Deng W, Wang F, Wei J, Du X, Zhou H, Yu H, Jiang Y, Wang QJ, Wang J.   +17 more
europepmc   +1 more source

A Comprehensive Meta‐Analysis and Review of Intraoperative Radiotherapy in Colorectal Cancer: Examining Radiation Dosage, Long‐Term Prognosis, and Treatment‐Related Complications

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background The effect of device type and radiation dose in intraoperative radiotherapy (IORT) for colorectal cancer is not well established. To explore this, we reviewed studies reporting postoperative complications, disease‐free survival, local control, and long‐term survival in patients treated with non‐implantable IORT techniques—IOERT, KV ...
Chuhan Guo, Shuyang Liu, Liangliang Li, Jiayi Zhao, Hongji Zhou, Hongqiang Liu, Tong Liu, Fujian Ji   +7 more
wiley   +1 more source

Patient-specific 3D-printed HDR surface brachytherapy for basal cell carcinoma in older patients: prospective feasibility and imaging response. [PDF]

Oncologist
Sobolewski P, Koper M, Poltorak M, Banatkiewicz P, Kolos M, Poltorak L, Szwast M, Walecka I.   +7 more
europepmc   +1 more source

‘Free to Be Me?’: Gender Role Norms Constrain Career Interests Less for Lesbian, Gay and Bisexual People Than for Heterosexual People

European Journal of Social Psychology, Volume 56, Issue 5, Page 903-921, August 2026.
ABSTRACT Societal gender role norms play a crucial role in shaping men's and women's career aspirations. However, prior research documenting this key role of gendered norms has primarily focused on heterosexual women and men in the global North‐West. Previous studies documenting differences in career interests by sexual orientation suggest that gender ...
Katharina Block, Jia Yue He, Maria I. T. Olsson, Sanne Van Grootel, Sarah E. Martiny, Toni Schmader, Colette Van Laar, Carolin Schuster, Loes Meeussen, Tabea Hässler, Alyssa Croft, Sheila X. R. Wee, Molly Shuyi Sun, Mare Ainsaar, Lianne Aarntzen, Magdalena Adamus, Ciara Atkinson, Mohamad Avicenna, Przemysław Bąbel, Markus Barth, Tessa M. Benson‐Greenwald, Edona Maloku, Jacques Berent, Hilary B. Bergsieker, Monica Biernat, Andreea G. Bîrneanu, Blerta Bodinaku, Janine Bosak, Jennifer Bosson, Marija Branković, Julius Burkauskas, Vladimíra Čavojová, Sapna Cheryan, Eunsoo Choi, Incheol Choi, Carlos C. Contreras‐Ibáñez, Andrew Coogan, Ivan Danyliuk, Ilan Dar‐Nimrod, Nilanjana Dasgupta, Soledad de Lemus, Thierry Devos, Marwan Diab, Amanda B. Diekman, Léïla Eisner, Anja Eller, Rasa Erentaitė, Denisa Fedáková, Renata Franc, Leire Gartzia, Alin Gavreliuc, Dana Gavreliuc, Julija Gecaite‐Stonciene, Adriana L. Germano, Ilaria Giovannelli, Renzo Gismondi Diaz, Lyudmila Gitikhmayeva, Abiy Menkir Gizaw, Biljana Gjoneska, Omar Martínez González, Roberto González, Isaac David Grijalva, Derya Güngör, Marie Gustafsson Sendén, William Hall, Charles Harb, Bushra Hassan, Diala R. Hawi, Levke Henningsen, Annedore Hoppe, Keiko Ishii, Ivana Jakšić, Alba Jasini, Jurgita Jurkevičienė, Kaltrina Kelmendi, Teri A. Kirby, Yoko Kitakaji, Natasza Kosakowska‐Berezecka, Inna Kozytska, Clara Kulich, Eva Kundtová‐Klocová, Filiz Kunuroglu, Christina Lapytskaia Aidy, Albert Lee, Anna Eneroth, Wilson López‐López, Liany Luzvinda, Fridanna Maricchiolo, Delphine Martinot, Rita Anne McNamara, Alyson Meister, Tizita Lemma Melka, Narseta Mickuviene, María Isabel Miranda‐Orrego, Thadeus Mkamwa, James Morandini, Thomas Morton, David Mrisho, Jana Nikitin, Sabine Otten, Maria Giuseppina Pacilli, Elizabeth Page‐Gould, Ana Perandrés‐Gómez, Jon Pizarro, Nada Pop‐Jordanova, Joanna Pyrkosz‐Pacyna, Samir Qouta, TamilSelvan Ramis, Nitya Rani, Sandrine Redersdorff, Isabelle Régner, Emma A. Renström, Adrian Rivera‐Rodriguez, Tania E. Rocha‐Sánchez, Rim Saab, Kiriko Sakata, Adil Samekin, Tracy Sánchez‐Pachecho, Carolin Scheifele, Marion K. Schulmeyer, Sabine Sczesny, David Sirlopú, Vanessa Smith‐Castro, Kadri Soo, Federica Spaccatini, Jennifer R. Steele, Melanie C. Steffens, Ines Sucic, Joseph Vandello, Laura Maria Velásquez‐Díaz, Melissa Vink, Eva Vives, Turuwark Zalalam Warkineh, Iris Žeželj, Xiaoxiao Zhang, Xian Zhao, Joel Anderson   +136 more
wiley   +1 more source

Design of a High Dynamic Range Acquisition System for Airborne VNIR Push-Broom Hyperspectral Camera. [PDF]

Sensors (Basel)
Feng H, Wang Y, He D, Zhang C, Li C.
europepmc   +1 more source

Gut microbiota‐targeted interventions for depression in adolescents and young adults: Mechanisms, evidence strength and clinical strategies—A narrative review

General Psychiatry, Volume 39, Issue 4, August 2026.
ABSTRACT Depression in adolescents and young adults is common, associated with substantial functional impairment and characterised by limited treatment efficacy. The microbiota–gut–brain (MGB) axis has emerged as a potential therapeutic target for depression.
Hanchen Hou, Yinan Li, Wanting Tang, Yiwen Gao, Yuanyuan Tian, Fei Chen, Lige Zhang, Jushuang Zhang, Xiaoxia Xu, Yao Li, Yi Li, Qingshan Wang, Lingli Liu, Teng Teng, Hao Wu, Xinyu Zhou   +15 more
wiley   +1 more source