Results 131 to 140 of about 10,931 (234)

Adenovirus Vector‐Mediated In Vivo Knock‐in Treatment of Neonatal Phenylketonuria Mice Using Terminally Cleaved Donor DNA

The Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
We successfully developed a highly efficient knock‐in adenovirus vector, AxPah‐6g‐cut. This vector cleaves not only the genomic target site but also the terminus of the donor DNA in the vector. When this vector was intravenously administered twice to phenylketonuria (Pahenu2) mice together with a Cas9‐expressing vector, AxCBCas9, it resulted in the ...
Megumi Yamaji, Hirotaka Tabata, Mariko Nakamura, Ryoko Fuse, Tadashi Okada, Shun‐Ichi Ohba, Tomokazu Ohishi, Manabu Kawada, Izumu Saito, Shigeto Sato, Tomoko Nakanishi   +10 more
wiley   +1 more source

Polish Brachytherapy Society clinical recommendations and expert consensus on radical high-dose-rate brachytherapy for prostate cancer. [PDF]

J Contemp Brachytherapy
Chyrek AJ, Hetnał M, Kukiełka A, Lelek P, Kluska A, Romaniszyn A, Samołyk-Kogaczewska N, Burchardt W, Cisek P, Krzysztofiak T, Kolbusz M, Kazalski D, Filipowski T, Kazberuk D, Szmigiel-Trzcin'ska A, Celarek K, Madej P, Konat-Ba Ska K, Lichon' K, Matys R, Bilski M, Burchardt E, Stankiewicz M, Chicheł A, Wojcieszek P.   +24 more
europepmc   +1 more source

A multidisciplinary experimental and methodological investigation of electron and proton minibeams in the framework of the INFN MIRO project

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background The clinical translation of Minibeam RT (MBRT) has recently started thanks to the first human treatments recently performed. However, despite experimental evidence, the impact of the dose distribution parameters involved on the magnitude of the effect itself and the underlying radiobiological mechanisms are still only partially ...
Francesco Romano, Francesca Cella Zanacchi, Esther Ciarrocchi, Gaia Franciosini, Giuliana Milluzzo, Emanuele Scifoni, Anna Vignati, Said Ahmad, Silvia Arezzini, Andrea Attili, Marco Battestini, Jacopo Bernardini, Matteo Bettanin, Alessandra Bisio, Maria Giuseppina Bisogni, Igor Bodrenko, Giulio Bordieri, Valentina Bravatà, Alberto Burattini, Massimo Camarda, Francesco Paolo Cammarata, Simone Capaccioli, Lorenzo Castelli, Andrea Cavalieri, Mariagrazia Celentano, Enrica Chiadroni, Francesco Giuseppe Cordoni, Elena Corvaia, Mario Costa, Alessandro Curcio, Eleonora Da Pozzo, Martina De Felice, Francesca Del Debbio, Francesco D'Errico, Maria Cristina D'Oca, Beatrice D'Orsi, Umberto Deut, Elisabetta Durisi, Maria Evelina Fantacci, Stefano Farina, Giuseppe Felici, Arianna Ferro, Luca Ficcadenti, Antonino Formuso, Giusi Irma Forte, Simona Giordanengo, Alessia Giuliano, Lucia Giuliano, Luca Lanzanò, Stefania Linsalata, Simone Lossano, Margherita Maffei, Michela Marafini, Maurizio Marrale, Maurizio Massa, Luigi Masturzo, Enrico Mazzoni, Mauro Migliorati, Felix Mas Milian, Luigi Minafra, Andrea Moggi, Diango Montalvan Olivares, Marco Montefiori, Matteo Morrocchi, Andrea Mostacci, Franco Mostardi, Chinonso Okpuwe, Fabiola Paiar, Luigi Palumbo, Vincenzo Patera, Jake Harold Pensavalle, Gaia Pucci, Flaminia Quattrini, Alessandra Retico, Valeria Rosso, Giorgio Russo, Roberto Sacchi, Alessio Sarti, Silvia Scalisi, Camilla Scapicchio, Angelo Schiavi, Paolo Stochino, Enrica Strettoi, Francesco Tommasino, Valentina Tozzini, Giacomo Traini, Gabriele Trovato, Alice Usai, Francesco Urso, Fabio Di Martino   +89 more
wiley   +1 more source

Trends in brachytherapy utilization in Canada from 2011 to 2020. [PDF]

Phys Imaging Radiat Oncol
Dumančić M, Zou Y, Glickman H, Kouraneh SG, Pater P, Alexander A, Aviles JEA, Cherpak A, Marchant K, Menon G, Morton D, Olding T, Paudel M, Rink A, Spadinger I, Enger SA.   +15 more
europepmc   +1 more source

Lighting up FLASH and beyond: TLD response across four orders of magnitude in proton dose rate

Medical Physics, Volume 53, Issue 8, August 2026.
ABSTRACT Background Thermoluminescent dosimeters (TLDs) are widely used for proton therapy dosimetry and remote audits. Yet their response under pulsed delivery and the ultrahigh dose rates relevant to proton FLASH remains incompletely characterized.
Fada Guan, Jason Tang, Ally Brookner, Hayden Scott, Ivan Vazquez, Sabrina Campelo, Daniel Liu, Jacob Mathew, Lawrence Bronk, Yuting Li, Paige Taylor   +10 more
wiley   +1 more source

Automated dual-camera DMD system for stereo optical sectioning imaging. [PDF]

Biomed Opt Express
Jiménez-Villar A, Ha S, Redd TK, Huang D, Kim D, Chen S.   +5 more
europepmc   +1 more source

Feasibility of convection‐enhanced delivery of unlabeled 225Ac for glioblastoma: Transport, dosimetry, and clonogenic survival modeling

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Glioblastoma (GB) is an aggressive primary brain tumor with local recurrence rates exceeding 90% and a five‐year survival rate of approximately 5%. Standard treatments such as surgical resection, external beam radiotherapy (EBRT), and chemotherapy often leave residual tumor cells that are resistant to therapy.
Maram El Sabri, Leyla Moghaddasi, Puthenparampil Wilson, Frank Saran, Eva Bezak   +4 more
wiley   +1 more source

Defining the optimal imaging time point for fluorescence-lifetime-based tumor identification using the non-targeting near-infrared dye indocyanine green and post-processed high-dynamic-range images. [PDF]

Biomed Opt Express
Janssen S, Van den Dries T, Lina Kheiro N, Lapauw T, de Geeter J, Sahakian S, Stroet M, Kuijk M, de Rooster H, Ingelberts H, Hernot S.   +10 more
europepmc   +1 more source

Cochlear Implant Complications and Outcomes: National Trends of the MAUDE Database From 2016 to 2024

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 2, Page 444-452, August 2026.
Abstract Objective As cochlear implant (CI) use expands, complications have become a growing concern. While prior studies analyzed CI failures, few have comprehensively assessed national complication temporal patterns and clinical outcomes. This study evaluates patient and device complication patterns and outcomes from 2016 to 2024.
Daniel R. S. Habib, Anthony E. Bishay, Michael W. S. Habib, Ankita Patro, Alexander J. Langerman, Aaron C. Moberly, David S. Haynes, Kareem O. Tawfik   +7 more
wiley   +1 more source

Advancing small-animal molecular imaging through multifaceted innovation. [PDF]

J Biomed Opt
Hong G, Ran C, Davis SC, Tichauer KM.
europepmc   +1 more source