Results 121 to 130 of about 47,768 (224)
Hemidesmosome Mutations Contribute to the Onset and Severity of Acquired Autoimmune Bullous Diseases
This study examined hemidesmosome assembly‐related genes in pemphigoid diseases, revealing variants linked to disease onset and severity. Functional analyses, including Caenorhabditis elegans models, Ker‐CT transcriptomics, human proteomics, etc., demonstrated that ITGA6 mutations destabilize hemidesmosomes, disrupt dermal–epidermal adhesion, and ...
Shan Cao +19 more
wiley +1 more source
Thermographic Behaviour of the Orbicularis Oris Muscle Under Different Provocative Tests
Study design showing the thermographic region of the orbicularis oris muscle (Picture 1), the foods used for chewing and the increase in mean temperature after the provocative tests (Picture 2). ABSTRACT Background Infrared thermography is an objective method for investigating muscle functioning, enabling inferences about physiology and therapeutics ...
Patrícia Vieira Salles +5 more
wiley +1 more source
Heterogeniety in electrochemical systems heavily influences device performance and durability. The study shows unique evidence of spatio‐operational heterogeneity in fuel cells via operando neutron and X‐ray tomography. Large variations in membrane thickness and hydration depend upon location and operating conditions, with implications on membrane ...
Pranay Shrestha +9 more
wiley +1 more source
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo +12 more
wiley +1 more source
Introduction: The cognitive function score (CFS) is a public scale for assessing the activities of daily living (ADL) in older adults with dementia in Japan.
Risa Hirata +20 more
doaj +1 more source
Robert J. Dukes, Saul J. Adelman
openaire +1 more source
Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore +4 more
wiley +1 more source
Activity Against Pythium insidiosum and Isolated Constituents of Cordia insignis Roots
This study investigates the roots of Cordia insignis in search of novel treatments for pythiosis, caused by the oomycete Pythium insidiosum. Seven compounds are isolated, including steroids, a saponin, a coumarin, a fatty acid, and a glycoside, the latter two are reported for the first time in the genus.
Rennan Carlos de Oliveira +8 more
wiley +1 more source

