Huntington disease exacerbates action impulses [PDF]
Frontiers in Psychology, 2023 BackgroundImpulsivity is a common clinical feature of Huntington disease (HD), but the underlying cognitive dynamics of impulse control in this population have not been well-studied.ObjectiveTo investigate the temporal dynamics of action impulse control ...
Shuhei Shiino +4 more
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Bariatric surgery and semaglutide in a youth with juvenile Huntington disease and severe obesity: a case report [PDF]
Journal of Medical Case ReportsBackground Managing severe obesity in youth with chronic, progressive conditions, such as juvenile Huntington disease, presents unique challenges. Juvenile Huntington disease, is characterized by rapid neurodegeneration, with most patients experiencing a
Alaina P. Vidmar +7 more
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The BACHD Rat Model of Huntington Disease Shows Signs of Fronto-Striatal Dysfunction in Two Operant Conditioning Tests of Short-Term Memory. [PDF]
PLoS ONE, 2017 The BACHD rat is a recently developed transgenic animal model of Huntington disease, a progressive neurodegenerative disorder characterized by extensive loss of striatal neurons.
Erik Karl Håkan Clemensson +3 more
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Exploring genetic factors involved in huntington disease age of onset. E2F2 as a new potential modifier gene [PDF]
, 2015 Age of onset (AO) of Huntington disease (HD) is mainly determined by the length of the CAG repeat expansion (CAGexp) in exon 1 of the HTT gene. Additional genetic variation has been suggested to contribute to AO, although the mechanism by which it could ...
Aguirre, Ana +17 more
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Predictors of persistence and adherence to deutetrabenazine among patients with Huntington disease or tardive dyskinesia [PDF]
Mental Health Clinician, 2023 Introduction Deutetrabenazine is approved for treatment of Huntington disease (HD)-related chorea and tardive dyskinesia (TD) in adults. Factors associated with deutetrabenazine persistence and adherence are not well understood.
Claassen Daniel O. MD +4 more
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Brain hypometabolism in rare genetic neurodegenerative disease: Niemann-Pick disease type C, spinocerebellar ataxia and Huntington disease assessed by FDG PET [PDF]
Asia Oceania Journal of Nuclear Medicine and Biology, 2021 Brain metabolic imaging using 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) with contemporaneous low-dose CT may be used to assess neurodegenerative diseases.
Yung Hsiang Kao +4 more
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Computer Methods and Programs in Biomedicine Update, 2023 Background: Unawareness of Huntington disease is prevalent where patients might have a denial of illness, less reporting of symptoms such as changes in behavior or cognitive impairment, or poor coping with the disease.
Nawal H Alharthi +2 more
doaj +1 more source
PAK in Alzheimer disease, Huntington disease and X-linked mental retardation. [PDF]
, 2012 Developmental cognitive deficits including X-linked mental retardation (XLMR) can be caused by mutations in P21-activated kinase 3 (PAK3) that disrupt actin dynamics in dendritic spines.
Cole, Greg M +3 more
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Neural Regeneration Research, 2015 MicroRNA-124 contributes to neurogenesis through regulating its targets, but its expression both in the brain of Huntington′s disease mouse models and patients is decreased.
Tian Liu +3 more
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Anesthetic management of a patient with Huntington's chorea -A case report- [PDF]
Korean Journal of Anesthesiology, 2013 Huntington's chorea is a rare hereditary disorder of the nervous system. It is inherited as an autosomal dominant disorder and is characterized by progressive chorea, dementia and psychiatric disturbances.
Jong-Man Kang +5 more
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