Results 41 to 50 of about 1,506 (219)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Preferences for Posttraumatic Osteoarthritis Prevention Strategies in Individuals With Anterior Cruciate Ligament Injury

open access: yesArthritis Care &Research, EarlyView.
Objective There is growing interest in evaluating new strategies to delay or prevent posttraumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury. Methods Participants with a history of
Kevin Kennedy   +9 more
wiley   +1 more source

Biopsychosocial determinants of hand function and its trajectories over five years in patients with hand osteoarthritis

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to investigate hand function trajectories over 5 years in primary hand osteoarthritis. Additionally, determinants of baseline and longitudinal hand function were assessed. Methods 538 patients with both baseline and 5‐year study visits were analyzed.
Annemiek V.E.M. Olde Meule   +4 more
wiley   +1 more source

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

open access: yesArthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk   +6 more
wiley   +1 more source

Approximate and Exact Solutions to Fractional Order Cauchy Reaction-Diffusion Equations by New Combine Techniques

open access: yesJournal of Mathematics, 2021
In this paper, we present a simple and efficient novel semianalytic method to acquire approximate and exact solutions for the fractional order Cauchy reaction-diffusion equations (CRDEs). The fractional order derivative operator is measured in the Caputo
Adnan Khan   +3 more
doaj   +1 more source

Discordance between patient and physician global assessments in early systemic sclerosis

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aims to identify factors associated with patient and physician global assessments and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (< 5 years) from the CONQUER registry were included.
Ellen Romich   +35 more
wiley   +1 more source

The Use of Sumudu Transform for Solving Certain Nonlinear Fractional Heat-Like Equations

open access: yesAbstract and Applied Analysis, 2013
We make use of the properties of the Sumudu transform to solve nonlinear fractional partial differential equations describing heat-like equation with variable coefficients.
Abdon Atangana, Adem Kılıçman
doaj   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg   +5 more
wiley   +1 more source

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