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Taxanes In Head and Neck Cancer
Future Oncology, 2005Paclitaxel and docetaxel are cytotoxic agents that act on the microtubule system and cause cell death. They are active in patients with squamous cell carcinoma of the head and neck region. They can be combined with other cytotoxic agents and radiotherapy with acceptable toxicity.
Schrijvers, Dirk, Vermorken, Jan B.
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Imaging in head and neck cancer
Current Treatment Options in Oncology, 2006The goals of imaging in head and neck cancer are to establish tumor extent and size, to assess nodal disease, to evaluate for perineural tumor spread, and to distinguish recurrent tumor from post-treatment changes. MRI is the preferred modality for assessment of nasopharyngeal, sinonasal, and parotid tumors, because of better contrast resolution, high ...
Zoran, Rumboldt +4 more
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Chemotherapy in head and neck cancer
Plastic and Reconstructive Surgery, 1966CHEMOTHERAPY in head and neck cancer had its clinical beginning in December 1942. Gilman and Philips, 1 Hunt and Philips, 2 and Goodman et al 3 while studying top secret nitrogen mustard and its biological behavior at Yale University discovered its cytotoxic role when absorbed. Following extensive studies on animal tumors it was first used in man under
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The chemotherapy of head and neck cancer
Anti-Cancer Drugs, 1999Studies of combination therapy [with agents such as cisplatin, 5-fluorouracil (5-FU) and methotrexate] have shown some improvements in response rate; however, no obvious survival advantage over monotherapy in the treatment of patients with metastatic or advanced locoregional cancer of the head and neck have been observed.
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JAMA, 1972
ABSTRACT The nasopharynx is a small boxlike structure at the top of the pharyngeal cylinder. Neoplasms spread in two directions, each leading to distinct neurological signs. Direct extension through the foramen lacerum into the cavernous sinus and middle fossa of the skull leads to the involvement of cranial nerves III, IV, V, VI, and more rarely ...
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ABSTRACT The nasopharynx is a small boxlike structure at the top of the pharyngeal cylinder. Neoplasms spread in two directions, each leading to distinct neurological signs. Direct extension through the foramen lacerum into the cavernous sinus and middle fossa of the skull leads to the involvement of cranial nerves III, IV, V, VI, and more rarely ...
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JAMA, 1971
ABSTRACT The malignant gradient increases as the origin of cancers moves posteriorly in the oral cavity and reaches the oropharynx (Fig 1, Fig 2, Table 1). Thus, cancers of the base of the tongue tend to be more extensive (60% to 70% are T3 and T4) and more aggressive than cancers in the oral portion of the tongue.2 The same is true of cancers of the ...
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ABSTRACT The malignant gradient increases as the origin of cancers moves posteriorly in the oral cavity and reaches the oropharynx (Fig 1, Fig 2, Table 1). Thus, cancers of the base of the tongue tend to be more extensive (60% to 70% are T3 and T4) and more aggressive than cancers in the oral portion of the tongue.2 The same is true of cancers of the ...
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Critical Reviews in Oncology/Hematology, 1998
L, Barzan, U, Tirelli, J L, Lefebvre
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L, Barzan, U, Tirelli, J L, Lefebvre
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Journal of the National Comprehensive Cancer Network, 2008
Arlene A, Forastiere +28 more
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Arlene A, Forastiere +28 more
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